Literature DB >> 31496497

Treating Vitamin D Deficiency and Insufficiency in Chronic Neck and Back Pain and Muscle Spasm: A Case Series.

Chunbo Cai1.   

Abstract

INTRODUCTION: The association between vitamin D deficiency or insufficiency and pain in the musculoskeletal system, especially in the neck and/or back regions, and/or muscle spasm is not well studied. The results of the limited studies have been mixed. CASE
PRESENTATION: The goal of this report is to examine the association between vitamin D deficiency and insufficiency and chronic neck and back pain and muscle spasm and the role of correction of vitamin D deficiency and insufficiency in the treatment of chronic pain and muscle spasm, especially in the neck and back regions. This case series reviewed medical records to identify patients with chronic pain (lasting from 6 months to 1 year) in the neck and back regions that improved significantly through the correction of the vitamin D deficiency or insufficiency. Patients were referred to the spine clinic of a tertiary hospital in a major metropolitan area in the Northwest by their primary care physicians after physical therapy and after first-tier pain medications, including nonsteroidal anti-inflammatory drugs, had failed. Some of the patients had epidural steroid injections without significant relief. The blood vitamin D level was tested at the clinical laboratory, and patients were given 50,000 IU of oral vitamin D once a week for 12 weeks. The main outcome measures were patient self-reported visual analog scale score and degree of muscle spasm. The 4 patients included in this series all had more than 70% improvement in their symptoms after taking 50,000 IU of vitamin D once a week for 12 weeks. DISCUSSION: Vitamin D deficiency and insufficiency can cause or worsen neck and back pain and muscle spasm. The correction of vitamin D deficiency and insufficiency plays an important role in the treatment of chronic neck and back pain and muscle spasm among patients having concurrent vitamin D deficiency and insufficiency because it can be prevented and treated easily.Given the high health care expenditure on the treatment of chronic neck and back pain, prompt and accurate diagnosis and treatment of vitamin D deficiency and insufficiency not only increase the quality of care but also reduce the cost.

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Year:  2019        PMID: 31496497      PMCID: PMC6730953          DOI: 10.7812/TPP/18.241

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  18 in total

Review 1.  The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis.

Authors:  Mark R Haussler; G Kerr Whitfield; Ichiro Kaneko; Ryan Forster; Rimpi Saini; Jui-Cheng Hsieh; Carol A Haussler; Peter W Jurutka
Journal:  Rev Endocr Metab Disord       Date:  2012-03       Impact factor: 6.514

Review 2.  Vitamin D deficiency.

Authors:  Michael F Holick
Journal:  N Engl J Med       Date:  2007-07-19       Impact factor: 91.245

3.  High prevalence of undetected vitamin D deficiency in an urban minority primary care practice.

Authors:  Linda S Kahn; Nikhil Satchidanand; Anil Kopparapu; Winston Goh; Sandra Yale; Chester H Fox
Journal:  J Natl Med Assoc       Date:  2011-05       Impact factor: 1.798

4.  Vitamin D Supplementation in Patients with Chronic Low Back Pain: An Open Label, Single Arm Clinical Trial.

Authors:  Babita Ghai; Dipika Bansal; Raju Kanukula; Kapil Gudala; Naresh Sachdeva; Saravdeep Singh Dhatt; Vishal Kumar
Journal:  Pain Physician       Date:  2017 Jan-Feb       Impact factor: 4.965

Review 5.  Vitamin D and human health: lessons from vitamin D receptor null mice.

Authors:  Roger Bouillon; Geert Carmeliet; Lieve Verlinden; Evelyne van Etten; Annemieke Verstuyf; Hilary F Luderer; Liesbet Lieben; Chantal Mathieu; Marie Demay
Journal:  Endocr Rev       Date:  2008-08-11       Impact factor: 19.871

Review 6.  The Effect of Abnormal Vitamin D Levels in Athletes.

Authors:  Jakub Sikora-Klak; Steven J Narvy; Justin Yang; Eric Makhni; F Daniel Kharrazi; Nima Mehran
Journal:  Perm J       Date:  2018

7.  Independence of 1,25-dihydroxyvitamin D3-mediated calcium transport from de novo RNA and protein synthesis.

Authors:  D D Bikle; D T Zolock; R L Morrissey; R H Herman
Journal:  J Biol Chem       Date:  1978-01-25       Impact factor: 5.157

Review 8.  High prevalence of vitamin D inadequacy and implications for health.

Authors:  Michael F Holick
Journal:  Mayo Clin Proc       Date:  2006-03       Impact factor: 7.616

Review 9.  Vitamin D in Pain Management.

Authors:  Maria Helde-Frankling; Linda Björkhem-Bergman
Journal:  Int J Mol Sci       Date:  2017-10-18       Impact factor: 5.923

10.  Assessment of Relationship between Vitamin D Deficiency and Pain Severity in Patients with Low Back Pain: A Retrospective, Observational Study.

Authors:  Erhan Gokcek; Ayhan Kaydu
Journal:  Anesth Essays Res       Date:  2018 Jul-Sep
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