Literature DB >> 31495454

The Sodium Channel Voltage Sensor Slides to Rest.

Vladimir Yarov-Yarovoy1, Paul DeCaen2.   

Abstract

Voltage-gated sodium channels (Navs) initiate the action potential waveforms in excitable cells. The molecular mechanisms controlling this process have been actively debated. New prokaryotic Nav structures by Wisedchaisri et al. have completed our understanding of the molecular conformations required for cellular electrical signaling, and provide key templates for research to examine eukaryotic Navs.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  gating charge; membrane protein; resting state; sodium channel; voltage-dependent channel gating; voltage-gated ion channel

Mesh：

Substances：

Year:  2019        PMID： 31495454      PMCID： PMC7373202          DOI： 10.1016/j.tips.2019.08.009

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  10 in total

1.  Structural basis for gating charge movement in the voltage sensor of a sodium channel.

Authors:  Vladimir Yarov-Yarovoy; Paul G DeCaen; Ruth E Westenbroek; Chien-Yuan Pan; Todd Scheuer; David Baker; William A Catterall
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-12       Impact factor: 11.205

2.  Measurement of current-voltage relations in the membrane of the giant axon of Loligo.

Authors:  A L HODGKIN; A F HUXLEY; B KATZ
Journal:  J Physiol       Date:  1952-04       Impact factor: 5.182

3.  Molecular model of the action potential sodium channel.

Authors:  H R Guy; P Seetharamulu
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

Review 4.  Molecular properties of voltage-sensitive sodium channels.

Authors:  W A Catterall
Journal:  Annu Rev Biochem       Date:  1986       Impact factor: 23.643

5.  Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution.

Authors:  Huaizong Shen; Qiang Zhou; Xiaojing Pan; Zhangqiang Li; Jianping Wu; Nieng Yan
Journal:  Science       Date:  2017-02-09       Impact factor: 47.728

6.  Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.

Authors:  Baron Chanda; Francisco Bezanilla
Journal:  J Gen Physiol       Date:  2002-11       Impact factor: 4.086

7.  Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.

Authors:  Goragot Wisedchaisri; Lige Tonggu; Eedann McCord; Tamer M Gamal El-Din; Liguo Wang; Ning Zheng; William A Catterall
Journal:  Cell       Date:  2019-07-25       Impact factor: 41.582

8.  The crystal structure of a voltage-gated sodium channel.

Authors:  Jian Payandeh; Todd Scheuer; Ning Zheng; William A Catterall
Journal:  Nature       Date:  2011-07-10       Impact factor: 49.962

9.  The complete structure of an activated open sodium channel.

Authors:  Altin Sula; Jennifer Booker; Leo C T Ng; Claire E Naylor; Paul G DeCaen; B A Wallace
Journal:  Nat Commun       Date:  2017-02-16       Impact factor: 14.919

10.  Charge movement associated with the opening and closing of the activation gates of the Na channels.

Authors:  C M Armstrong; F Bezanilla
Journal:  J Gen Physiol       Date:  1974-05       Impact factor: 4.086
  10 in total
  1 in total

Review 1.  Roles for Countercharge in the Voltage Sensor Domain of Ion Channels.

Authors:  James R Groome; Landon Bayless-Edwards
Journal:  Front Pharmacol       Date:  2020-02-28       Impact factor: 5.810
  1 in total

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