Mahbubeh Haddad1, Fereshte Sheybani1,2, Mahnaz Arian1, Masoumeh Gharib3. 1. Department of Infectious Diseases and Tropical Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. 2. Imam Reza Clinical Research Unit, Mashhad University of Medical Sciences, Mashhad, Iran. 3. Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.