Literature DB >> 31494779

The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis.

Vida Vafaizadeh1, Emilia Peuhu2,3, Marja L Mikkola4, Walid T Khaled5, Mohamed Bentires-Alj6, Zuzana Koledova7.   

Abstract

The eleventh annual workshop of the European Network for Breast Development and Cancer, Methods in mammary gland biology and breast cancer, took place on the 16th to 18th of May 2019 in Weggis, Switzerland. The main topics of the meeting were high resolution genomics and proteomics for the study of mammary gland development and cancer, breast cancer signaling, tumor microenvironment, preclinical models of breast cancer, and tissue morphogenesis. Exciting novel findings in, or highly relevant to, mammary gland biology and breast cancer field were presented, with insights into the methods used to obtain them. Among others, the discussed methods included single-cell RNA sequencing, genetic barcoding, lineage tracing, spatial transcriptomics, optogenetics, genetic mouse models and organoids.

Entities:  

Keywords:  Barcoding; Proteomics; Signaling; Tissue morphogenesis; Transcriptomics; Tumor microenvironment

Mesh:

Year:  2019        PMID: 31494779     DOI: 10.1007/s10911-019-09436-0

Source DB:  PubMed          Journal:  J Mammary Gland Biol Neoplasia        ISSN: 1083-3021            Impact factor:   2.673


  32 in total

Review 1.  Molecular mechanisms of asymmetric divisions in mammary stem cells.

Authors:  Angela Santoro; Thalia Vlachou; Manuel Carminati; Pier Giuseppe Pelicci; Marina Mapelli
Journal:  EMBO Rep       Date:  2016-11-21       Impact factor: 8.807

2.  Visualization and analysis of gene expression in tissue sections by spatial transcriptomics.

Authors:  Patrik L Ståhl; Fredrik Salmén; Sanja Vickovic; Anna Lundmark; José Fernández Navarro; Jens Magnusson; Stefania Giacomello; Michaela Asp; Jakub O Westholm; Mikael Huss; Annelie Mollbrink; Sten Linnarsson; Simone Codeluppi; Åke Borg; Fredrik Pontén; Paul Igor Costea; Pelin Sahlén; Jan Mulder; Olaf Bergmann; Joakim Lundeberg; Jonas Frisén
Journal:  Science       Date:  2016-07-01       Impact factor: 47.728

3.  BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance.

Authors:  Alexandra A Duarte; Ewa Gogola; Norman Sachs; Marco Barazas; Stefano Annunziato; Julian R de Ruiter; Arno Velds; Sohvi Blatter; Julia M Houthuijzen; Marieke van de Ven; Hans Clevers; Piet Borst; Jos Jonkers; Sven Rottenberg
Journal:  Nat Methods       Date:  2017-12-11       Impact factor: 28.547

4.  ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

Authors:  Alejandro E Mayorca-Guiliani; Chris D Madsen; Thomas R Cox; Edward R Horton; Freja A Venning; Janine T Erler
Journal:  Nat Med       Date:  2017-06-12       Impact factor: 53.440

5.  Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells.

Authors:  Cedric Gaggioli; Steven Hooper; Cristina Hidalgo-Carcedo; Robert Grosse; John F Marshall; Kevin Harrington; Erik Sahai
Journal:  Nat Cell Biol       Date:  2007-11-25       Impact factor: 28.824

6.  Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration.

Authors:  I Acerbi; L Cassereau; I Dean; Q Shi; A Au; C Park; Y Y Chen; J Liphardt; E S Hwang; V M Weaver
Journal:  Integr Biol (Camb)       Date:  2015-05-11       Impact factor: 2.192

7.  Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells.

Authors:  Aline Wuidart; Marielle Ousset; Steffen Rulands; Benjamin D Simons; Alexandra Van Keymeulen; Cédric Blanpain
Journal:  Genes Dev       Date:  2016-06-09       Impact factor: 11.361

8.  Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.

Authors:  Bruno M Simões; Ciara S O'Brien; Rachel Eyre; Andreia Silva; Ling Yu; Aida Sarmiento-Castro; Denis G Alférez; Kath Spence; Angélica Santiago-Gómez; Francesca Chemi; Ahmet Acar; Ashu Gandhi; Anthony Howell; Keith Brennan; Lisa Rydén; Stefania Catalano; Sebastiano Andó; Julia Gee; Ahmet Ucar; Andrew H Sims; Elisabetta Marangoni; Gillian Farnie; Göran Landberg; Sacha J Howell; Robert B Clarke
Journal:  Cell Rep       Date:  2015-09-17       Impact factor: 9.423

9.  Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.

Authors:  Bhupinder Pal; Yunshun Chen; François Vaillant; Paul Jamieson; Lavinia Gordon; Anne C Rios; Stephen Wilcox; Naiyang Fu; Kevin He Liu; Felicity C Jackling; Melissa J Davis; Geoffrey J Lindeman; Gordon K Smyth; Jane E Visvader
Journal:  Nat Commun       Date:  2017-11-20       Impact factor: 14.919

10.  ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1.

Authors:  Melissa Berto; Valerie Jean; Wilbert Zwart; Didier Picard
Journal:  Life Sci Alliance       Date:  2018-06-07
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  1 in total

1.  Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer.

Authors:  Elsa Charifou; Gunnhildur Asta Traustadottir; Mohamed Bentires-Alj; Beatrice Howard; Alexandra Van Keymeulen
Journal:  J Mammary Gland Biol Neoplasia       Date:  2021-08-26       Impact factor: 2.673

  1 in total

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