Literature DB >> 31494130

Chlorhexidine-based decolonization to reduce healthcare-associated infections and multidrug-resistant organisms (MDROs): who, what, where, when, and why?

S S Huang1.   

Abstract

Body surface decolonization with chlorhexidine bathing and nasal mupirocin has become a simple solution for prevention of healthcare-associated infections. The clinical trial evidence for this practice will be reviewed to understand who benefits from this practice, for what reasons, and at what times. The method of bathing and nasal decolonization will also be discussed as proper application is needed for maximal effectiveness. Finally, the conflict between current effectiveness and future potential for fueling resistance is considered.
Copyright © 2019 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Chlorhexidine; Decolonization; MRSA; Multidrug-resistant bacteria

Mesh：

Substances：

Year:  2019        PMID： 31494130     DOI： 10.1016/j.jhin.2019.08.025

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN： 0195-6701            Impact factor:   3.926


  9 in total

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2.  Infection prevention requirements for the medical care of immunosuppressed patients: recommendations of the Commission for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute.

Authors: 
Journal:  GMS Hyg Infect Control       Date:  2022-04-13

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Journal:  Mycoses       Date:  2021-06-05       Impact factor: 4.931

4.  Real-world experience of how chlorhexidine bathing affects the acquisition and incidence of vancomycin-resistant enterococci (VRE) in a medical intensive care unit with VRE endemicity: a prospective interrupted time-series study.

Authors:  Jin Woong Suh; Nam Hee Kim; Min Jung Lee; Seoung Eun Lee; Byung Chul Chun; Chang Kyu Lee; Juneyoung Lee; Jong Hun Kim; Sun Bean Kim; Young Kyung Yoon; Jang Wook Sohn; Min Ja Kim
Journal:  Antimicrob Resist Infect Control       Date:  2021-11-10       Impact factor: 4.887

5.  Implementing daily chlorhexidine gluconate treatment for the prevention of healthcare-associated infections in non-intensive care settings: A multiple case analysis.

Authors:  Jackson S Musuuza; Tonya J Roberts; Ann Schoofs Hundt; Pascale Carayon; Michele L Zimbric; Valeri Schuetz; Mel Reppen; Windy Smith; Kirsten Koffarnus; Roger L Brown; Jason Bowling; Kat Jalali; Nasia Safdar
Journal:  PLoS One       Date:  2020-04-24       Impact factor: 3.240

6. 

Authors: 
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2021-02       Impact factor: 1.513

7.  Co-Lateral Effect of Octenidine, Chlorhexidine and Colistin Selective Pressures on Four Enterobacterial Species: A Comparative Genomic Analysis.

Authors:  Mathilde Lescat; Mélanie Magnan; Sonia Kenmoe; Patrice Nordmann; Laurent Poirel
Journal:  Antibiotics (Basel)       Date:  2021-12-31

8.  Effectiveness of a Multicomponent Intervention to Reduce Multidrug-Resistant Organisms in Nursing Homes: A Cluster Randomized Clinical Trial.

Authors:  Lona Mody; Kyle J Gontjes; Marco Cassone; Kristen E Gibson; Bonnie J Lansing; Julia Mantey; Mohammed Kabeto; Andrzej Galecki; Lillian Min
Journal:  JAMA Netw Open       Date:  2021-07-01

9.  Modeling Interventions to Reduce the Spread of Multidrug-Resistant Organisms Between Health Care Facilities in a Region.

Authors:  Sarah M Bartsch; Kim F Wong; Leslie E Mueller; Gabrielle M Gussin; James A McKinnell; Thomas Tjoa; Patrick T Wedlock; Jiayi He; Justin Chang; Shruti K Gohil; Loren G Miller; Susan S Huang; Bruce Y Lee
Journal:  JAMA Netw Open       Date:  2021-08-02
  9 in total

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