| Literature DB >> 3149401 |
B Lannes1, G Micheletti, M Vergnes, C Marescaux, A Depaulis, J M Warter.
Abstract
The relationship between states of vigilance and spike and wave discharges (SWD) was examined during 12 hours in 4 Wistar rats from a strain bred for spontaneous generalized non-convulsant seizures. On the basis of cortical and hippocampal EEG and EMG activity, wakefulness (W), slow wave sleep (SWS) and paradoxical sleep (REM) were distinguished. Of the SWD 86% occurred during quiet W, 14% during the first minutes of SWS. No SWD occurred during active wakefulness and they were exceptional during REM. These results show that the states of quiet W and transitional states favour the SWD in rats with petit mal-like epilepsy, as in human petit mal.Entities:
Mesh：
Year: 1988 PMID： 3149401 DOI： 10.1016/0304-3940(88)90293-5
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046