Hyacinthe Zamané1,2, Fabienne Sanou3, Sibraogo Kiemtoré1,2, Dantola Paul Kain1,2, Arnaud Kiswendsida Sawadogo4, Blandine Bonané-Thiéba1,2. 1. Department of Gynecology and Obstetrics, Teaching Hospital Yalgado Ouedraogo, Ouagadougou, Burkina Faso. 2. University Ouaga 1 Pr Joseph Ki Zerbo, Ouagadougou, Burkina Faso. 3. Department of Oncology and Hematology, Bogodo District Hospital, Ouagadougou, Burkina Faso. 4. Department of Medicine, Saint Camille Hospital, Ouagadougou, Burkina Faso.
Abstract
OBJECTIVE: To study the contribution of blood transfusion management in the improvement of maternal and perinatal outcomes in pregnant women with sickle cell disease in Ouagadougou. METHODS: A cross-sectional retrospective study with data collected from February 2012 to January 2014 was used. Patients were differentiated into three groups: patients with at least one exchange transfusion, patients who received blood transfusion, and patients who did not receive any transfusion. Data were collected from patients' patient care documents. RESULTS: One hundred and sixty-four patients were included, of whom 53 were in the first group, 32 in the second group, and 79 in the third group. Maternal complications in the last trimester of pregnancy were significantly less important (P=0.000) in the first group (58.5%) than in the second (78.5%) and third group (91.1%). The same trend was observed for postpartum maternal mortality (5.7%; 12.5%; 12.6%; P=0.009). Fetal complications such as preterm birth and early neonatal death were lower in the first group (15.1%; 1.8%) than in the second (40.6%; 23.1%) and third group (32.9%; 7.6%). CONCLUSION: Prophylactic blood transfusion is an important part of the management of pregnant patients with sickle cell disease.
OBJECTIVE: To study the contribution of blood transfusion management in the improvement of maternal and perinatal outcomes in pregnant women with sickle cell disease in Ouagadougou. METHODS: A cross-sectional retrospective study with data collected from February 2012 to January 2014 was used. Patients were differentiated into three groups: patients with at least one exchange transfusion, patients who received blood transfusion, and patients who did not receive any transfusion. Data were collected from patients' patient care documents. RESULTS: One hundred and sixty-four patients were included, of whom 53 were in the first group, 32 in the second group, and 79 in the third group. Maternal complications in the last trimester of pregnancy were significantly less important (P=0.000) in the first group (58.5%) than in the second (78.5%) and third group (91.1%). The same trend was observed for postpartum maternal mortality (5.7%; 12.5%; 12.6%; P=0.009). Fetal complications such as preterm birth and early neonatal death were lower in the first group (15.1%; 1.8%) than in the second (40.6%; 23.1%) and third group (32.9%; 7.6%). CONCLUSION: Prophylactic blood transfusion is an important part of the management of pregnant patients with sickle cell disease.
Authors: F O Galiba Atipo Tsiba; C Itoua; C Ehourossika; N Y Ngakegni; G Buambo; N S B Potokoue Mpia; A Elira Dokekias Journal: Anemia Date: 2020-09-15