José Alexandre Mendonça1, Sibel Zehra Aydin2, Maria-Antonietta D'Agostino3,4. 1. Department of Rheumatology and Postgraduate Program of the Pontifical Catholic, University of Campinas, Rua da Fazenda, 125, Condomínio Dálias, casa 10, Residencial Vila Flora, Sumaré, São Paulo, 13175665, Brazil. mendoncaja.us@gmail.com. 2. The Ottawa Hospital Research Institute, Division of Rheumatology, University of Ottawa, Ottawa, ON, Canada. 3. APHP, Hôpital Ambroise Paré, Rheumatology Department, 92100, Boulogne-Billancourt, France. 4. INSERM U1173, Laboratoire d'Excellence INFLAMEX, UFR Simone Veil, Versailles-Saint-Quentin University, 78180, Saint-Quentin-en-Yvelines, France.
Abstract
BACKGROUND: Nail involvement has been described as a key clinical feature for both psoriasis (PsO) and psoriatic arthritis (PsA) and is an important risk factor in PsA. Thus, early diagnosis of nail involvement may be essential for better management of PsO and PsA. Ultrasonography is considered a highly promising method to visualize nail disease. The main aim of this review was to evaluate the use of ultrasonography for the diagnosis of nail disease in patients with PsO and PsA by reviewing ultrasound parameters with the best diagnostic accuracy. Main body of the abstract: A systematic search was performed in MEDLINE via the PubMed and LILACS databases. Conference proceedings of relevant rheumatology scientific meetings were also screened. RESULTS: After applying eligibility criteria, only 13 articles and 5 abstracts were included in this review. The selected studies showed a huge variability in evaluation methods (and therefore in the results) and were mainly focused on the assessment of nails ultrasound parameters that may differ among patients and healthy controls, especially the morphological aspects in B-mode ultrasonography and vascularization of the nail bed by Doppler ultrasonography. Our research indicated that the evaluation of nail disease in PsO and PsA is still underrepresented in the literature, probably reflecting a restricted use in clinical practice, despite the widespread use of ultrasonography in the management of chronic arthritis. SHORT CONCLUSIONS: Despite the potential relevance of ultrasonography for the diagnosis of nail disease, additional studies are needed to determine which features are more reliable and clinically pertinent to ensure accuracy in the evaluation of nail involvement in PsO and PsA.
BACKGROUND:Nail involvement has been described as a key clinical feature for both psoriasis (PsO) and psoriatic arthritis (PsA) and is an important risk factor in PsA. Thus, early diagnosis of nail involvement may be essential for better management of PsO and PsA. Ultrasonography is considered a highly promising method to visualize nail disease. The main aim of this review was to evaluate the use of ultrasonography for the diagnosis of nail disease in patients with PsO and PsA by reviewing ultrasound parameters with the best diagnostic accuracy. Main body of the abstract: A systematic search was performed in MEDLINE via the PubMed and LILACS databases. Conference proceedings of relevant rheumatology scientific meetings were also screened. RESULTS: After applying eligibility criteria, only 13 articles and 5 abstracts were included in this review. The selected studies showed a huge variability in evaluation methods (and therefore in the results) and were mainly focused on the assessment of nails ultrasound parameters that may differ among patients and healthy controls, especially the morphological aspects in B-mode ultrasonography and vascularization of the nail bed by Doppler ultrasonography. Our research indicated that the evaluation of nail disease in PsO and PsA is still underrepresented in the literature, probably reflecting a restricted use in clinical practice, despite the widespread use of ultrasonography in the management of chronic arthritis. SHORT CONCLUSIONS: Despite the potential relevance of ultrasonography for the diagnosis of nail disease, additional studies are needed to determine which features are more reliable and clinically pertinent to ensure accuracy in the evaluation of nail involvement in PsO and PsA.
Authors: Bhumesh Kumar Katakam; Malathi Munisamy; T Narayana Rao; Minu Jose Chiramel; Maitreyee Panda; Sandeep Gupta; Ranugha Pss; K A Seetharam Journal: Indian Dermatol Online J Date: 2021-11-25
Authors: José Alexandre Mendonça; Lucas Nogueira Pansani; Mateus Basso Mimoto; Igor Tadeu Garcia Ferreira; Fernanda Bertucci Sanches; Thais de Campos Ferreira Pinto; Vania Aparecida Leandro-Merhi; José Luis Braga de Aquino Journal: Drugs Context Date: 2020-06-03