Yanran Duan1, Yi Liao2, Hongyan Li1, Siyu Yan1, Zhiguang Zhao2, Shuyuan Yu3, Yingbin Fu2, Zhihui Wang1, Ping Yin4, Jinquan Cheng5, Hongwei Jiang6. 1. Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 2. Department of Public Health Promotion, Shenzhen Center for Disease Control and Prevention, Shenzhen, China. 3. Department of environment and health, Shenzhen Center for Disease Control and Prevention, Shenzhen, China. 4. Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: pingyin2000@126.com. 5. Shenzhen Center for Disease Control and Prevention, Shenzhen, China. Electronic address: cjinquan@szcdc.net. 6. Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: jhwccc0@sina.com.
Abstract
BACKGROUND: The intricate association of mortality risk with ambient air pollution and temperature is of growing concern. Little is known regarding effect of changes in season and temperature on daily cardiovascular mortality associated with air pollutant nitrogen dioxide (NO2). OBJECTIVES: Our study aimed to assess the effect of NO2 on cardiovascular mortality modified by season and daily air temperature in the effect, and further to identify the population highly susceptible to cardiovascular mortality associated with NO2 and air temperature. METHODS: We collected daily cause-specific death data, weather conditions, and air pollutant concentrations in Shenzhen from 2013 to 2017. Distributed-lag linear models were employed to analyze the effect of season on the NO2-associated mortality. Furthermore, generalized additive models were combined with stratification parametric analysis to estimate the interaction effect of NO2 with air temperature on cardiovascular mortality. RESULTS: In the cold season, the percentage increase in daily mortality for every 10 μg/m3 increment in NO2 concentration over lags of 0-2 days was 4.45% (95% CI: 2.71-6.21%). However, no statistically significant effect of NO2 was observed in the warm season. Compared with high-temperature days (>median temperature), a 3.51% increase in mortality (95% CI: 2.04-5.01%) over low-temperature days (≤median temperature) for the same increase in NO2 was significant. Air temperature modified the effect of NO2 on daily mortality by 4.08% (95% CI: 2.28-5.91%) for the elderly (age ≥ 65 years) on low-temperature days vs. -0.82% (95% CI: -3.88-2.34%) on high-temperature days, and 3.38% (95% CI: 1.50-5.29%) for males on low-temperature days vs. -0.73% (95% CI: -3.83-2.47%) on high air temperature days. CONCLUSIONS: The cold season and low temperatures could significantly enhance the effect of NO2 on cardiovascular mortality. The elderly and males suffering from cardiovascular disease should take precautions against low temperature and NO2 air pollution.
BACKGROUND: The intricate association of mortality risk with ambient air pollution and temperature is of growing concern. Little is known regarding effect of changes in season and temperature on daily cardiovascular mortality associated with air pollutant nitrogen dioxide (NO2). OBJECTIVES: Our study aimed to assess the effect of NO2 on cardiovascular mortality modified by season and daily air temperature in the effect, and further to identify the population highly susceptible to cardiovascular mortality associated with NO2 and air temperature. METHODS: We collected daily cause-specific death data, weather conditions, and air pollutant concentrations in Shenzhen from 2013 to 2017. Distributed-lag linear models were employed to analyze the effect of season on the NO2-associated mortality. Furthermore, generalized additive models were combined with stratification parametric analysis to estimate the interaction effect of NO2 with air temperature on cardiovascular mortality. RESULTS: In the cold season, the percentage increase in daily mortality for every 10 μg/m3 increment in NO2 concentration over lags of 0-2 days was 4.45% (95% CI: 2.71-6.21%). However, no statistically significant effect of NO2 was observed in the warm season. Compared with high-temperature days (>median temperature), a 3.51% increase in mortality (95% CI: 2.04-5.01%) over low-temperature days (≤median temperature) for the same increase in NO2 was significant. Air temperature modified the effect of NO2 on daily mortality by 4.08% (95% CI: 2.28-5.91%) for the elderly (age ≥ 65 years) on low-temperature days vs. -0.82% (95% CI: -3.88-2.34%) on high-temperature days, and 3.38% (95% CI: 1.50-5.29%) for males on low-temperature days vs. -0.73% (95% CI: -3.83-2.47%) on high air temperature days. CONCLUSIONS: The cold season and low temperatures could significantly enhance the effect of NO2 on cardiovascular mortality. The elderly and males suffering from cardiovascular disease should take precautions against low temperature and NO2 air pollution.
Authors: Yaoyao Qian; Haomin Li; Andrew Rosenberg; Qiulun Li; Jeremy Sarnat; Stefania Papatheodorou; Joel Schwartz; Donghai Liang; Yang Liu; Pengfei Liu; Liuhua Shi Journal: Environ Health Perspect Date: 2021-12-28 Impact factor: 9.031
Authors: Chengzhen Meng; Fang Ke; Yao Xiao; Suli Huang; Yanran Duan; Gang Liu; Shuyuan Yu; Yingbin Fu; Ji Peng; Jinquan Cheng; Ping Yin Journal: Front Public Health Date: 2022-01-24
Authors: Yueling Ma; Li Yue; Jiangtao Liu; Xiaotao He; Lanyu Li; Jingping Niu; Bin Luo Journal: BMC Public Health Date: 2020-06-02 Impact factor: 3.295
Authors: Raphael Romano Bruno; Bernhard Wernly; Maryna Masyuk; Johanna M Muessig; Rene Schiffner; Laura Bäz; Christian Schulze; Marcus Franz; Malte Kelm; Christian Jung Journal: Wien Med Wochenschr Date: 2021-03-18