Literature DB >> 31486028

Introduction to Oncolytic Virotherapy.

Christine E Engeland1, John C Bell2,3.   

Abstract

Oncolytic viruses exploit key hallmarks of cancer for replication in malignant cells, leading to tumor cell lysis, modulation of the tumor microenvironment and in situ vaccination effects. Diverse virus platforms have been developed as oncolytic vectors and designed for improved tumor specificity, intratumoral spread, therapeutic gene delivery and especially as targeted cancer immunotherapeutics. This chapter provides a concise overview of the basic principles as well as current progress in preclinical and clinical studies of oncolytic virotherapy.

Entities:  

Keywords:  Cancer gene therapy; Cancer immunotherapy; Oncolytic viruses; Tumor targeting; Viral vectors

Year:  2020        PMID： 31486028     DOI： 10.1007/978-1-4939-9794-7_1

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  9 in total

1.  A Brief Introduction to Current Cancer Gene Therapy.

Authors:  Dennis Kobelt; Jessica Pahle; Wolfgang Walther
Journal:  Methods Mol Biol       Date:  2022

2.  Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy.

Authors:  Peter D Koch; Christopher B Rodell; Rainer H Kohler; Mikael J Pittet; Ralph Weissleder
Journal:  Cell Chem Biol       Date:  2020-01-02       Impact factor: 8.116

3.  Oncolytic viral immunotherapy in the time of COVID-19.

Authors:  David Olagnier; Tommy Alain
Journal:  Cytokine Growth Factor Rev       Date:  2020-11-04       Impact factor: 7.638

4.  Assessing and Overcoming Resistance Phenomena against a Genetically Modified Vaccinia Virus in Selected Cancer Cell Lines.

Authors:  Susanne Berchtold; Julia Beil; Christian Raff; Irina Smirnow; Martina Schell; Janina D'Alvise; Silvia Gross; Ulrich M Lauer
Journal:  Int J Mol Sci       Date:  2020-10-15       Impact factor: 5.923

Review 5.  Mesenchymal stem cell carriers enhance anti-tumor efficacy of oncolytic virotherapy.

Authors:  Xianyao Wang; Xing Zhao; Zhixu He
Journal:  Oncol Lett       Date:  2021-01-28       Impact factor: 2.967

Review 6.  Is immunotherapy in the future of therapeutic management of sarcomas?

Authors:  Ottavia Clemente; Alessandro Ottaiano; Giuseppe Di Lorenzo; Alessandra Bracigliano; Sabrina Lamia; Lucia Cannella; Antonio Pizzolorusso; Massimiliano Di Marzo; Mariachiara Santorsola; Annarosaria De Chiara; Flavio Fazioli; Salvatore Tafuto
Journal:  J Transl Med       Date:  2021-04-26       Impact factor: 5.531

Review 7.  Oncolytic Virotherapy and Microenvironment in Multiple Myeloma.

Authors:  Valentina Marchica; Federica Costa; Gaetano Donofrio; Nicola Giuliani
Journal:  Int J Mol Sci       Date:  2021-02-24       Impact factor: 5.923

Review 8.  The use of oncolytic virotherapy in the neoadjuvant setting.

Authors:  Raquela J Thomas; Eric Bartee
Journal:  J Immunother Cancer       Date:  2022-04       Impact factor: 13.751

Review 9.  Updates on mechanistic insights and targeting of tumour metastasis.

Authors:  Zeru Feng; Qiuxuan Yu; Ting Zhang; Wanpeng Tie; Jing Li; Xikun Zhou
Journal:  J Cell Mol Med       Date:  2020-01-19       Impact factor: 5.310
  9 in total

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