Literature DB >> 31485149

Bleeding and Elevated INR Secondary to Concomitant Tramadol and Warfarin Administration.

Keith T Veltri, William A Olsufka.   

Abstract

The exact mechanism of a tramadol-warfarin interaction has not been fully determined. The authors present a case study that illustrates the risks.

Entities:  

Year:  2019        PMID： 31485149      PMCID： PMC6705477     

Source DB:  PubMed          Journal:  P T        ISSN： 1052-1372


  16 in total

1.  Administration of tramadol or ibuprofen increases the INR level in patients on warfarin.

Authors:  Jacob Juel; Torben Brøchner Pedersen; Christian Sigvald Langfrits; Svend Eggert Jensen
Journal:  Eur J Clin Pharmacol       Date:  2012-06-17       Impact factor: 2.953

2.  SSRIs and gastrointestinal bleeding.

Authors:  Carol Paton; I Nicol Ferrier
Journal:  BMJ       Date:  2005-09-10

3.  PharmGKB summary: tramadol pathway.

Authors:  Li Gong; Ulrike M Stamer; Mladen V Tzvetkov; Russ B Altman; Teri E Klein
Journal:  Pharmacogenet Genomics       Date:  2014-07       Impact factor: 2.089

4.  Successful anticoagulation and continuation of tramadol therapy in the setting of a tramadol-warfarin interaction.

Authors:  Peter A Dumo; Luba A Kielbasa
Journal:  Pharmacotherapy       Date:  2006-11       Impact factor: 4.705

5.  [Pharmaceutical care of serious bleeding induced by tramadol-warfarin interaction: a case report].

Authors:  Shu-jie Dong; Ting Zhang; Yan Li; Suo-di Zhai
Journal:  Beijing Da Xue Xue Bao Yi Xue Ban       Date:  2014-10-18

6.  Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.

Authors:  V Subrahmanyam; A B Renwick; D G Walters; P J Young; R J Price; A P Tonelli; B G Lake
Journal:  Drug Metab Dispos       Date:  2001-08       Impact factor: 3.922

Review 7.  Effects of selective serotonin reuptake inhibitors on platelet function: mechanisms, clinical outcomes and implications for use in elderly patients.

Authors:  Francisco J de Abajo
Journal:  Drugs Aging       Date:  2011-05-01       Impact factor: 3.923

8.  Concurrent use of tramadol and oral vitamin K antagonists and the risk of excessive anticoagulation: a register-based nested case-control study.

Authors:  Anton Pottegård; Peter M Meegaard; Line H V Holck; Rene dePont Christensen; Hanne Madsen; Jesper Hallas
Journal:  Eur J Clin Pharmacol       Date:  2012-07-31       Impact factor: 2.953

9.  Increased liability of tramadol-warfarin interaction in individuals with mutations in the cytochrome P450 2D6 gene.

Authors:  Karin Hedenmalm; Jonatan D Lindh; Juliette Säwe; Anders Rane
Journal:  Eur J Clin Pharmacol       Date:  2004-06-10       Impact factor: 2.953

10.  Serotonin transporter polymorphism and bleeding time during SSRI therapy.

Authors:  Dahlia M C Hougardy; Toine C G Egberts; Fedde van der Graaf; Vincent J Brenninkmeijer; Luc J J Derijks
Journal:  Br J Clin Pharmacol       Date:  2008-02-12       Impact factor: 4.335
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