| Literature DB >> 31484051 |
Johannes V Swinnen1, Jonas Dehairs2, Ali Talebi2.
Abstract
Enhanced growth factor signaling is a hallmark of cancer, allowing cancer cells to thrive in a challenging environment. In this issue of Cell Metabolism, Bi et al. (2019) identify LPCAT1, a key membrane lipid remodeling enzyme, as a central link between genetically driven growth factor receptor expression, signaling, and tumor growth, highlighting lipid remodeling as a therapeutic target in cancer.Entities:
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Year: 2019 PMID： 31484051 DOI： 10.1016/j.cmet.2019.08.016
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287