Literature DB >> 31482738

Advances of Wnt signalling pathway in dental development and potential clinical application.

Xi Lu1, Jun Yang1, Shouliang Zhao1, Shangfeng Liu1.   

Abstract

Wnt signalling pathway is widely studied in many processes of biological development, like embryogenesis, tissue homeostasis and wound repair. It is universally known that Wnt signalling pathway plays an important role in tooth development. Here, we summarized the function of Wnt signalling pathway during tooth initiation, crown morphogenesis, root formation, and discussed the therapeutic potential of Wnt modulators.

Entities:  

Keywords:  Dentin regeneration; Wnt signalling; crown morphogenesis; root formation

Mesh：

Substances：

Year:  2019        PMID： 31482738      PMCID： PMC6804710          DOI： 10.1080/15476278.2019.1656996

Source DB:  PubMed          Journal:  Organogenesis        ISSN： 1547-6278            Impact factor:   2.500


  75 in total

1.  Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.

Authors:  Masashi Kobayashi; Shosei Kishida; Akimasa Fukui; Tatsuo Michiue; Yoichi Miyamoto; Tetsuji Okamoto; Yoshihiro Yoneda; Makoto Asashima; Akira Kikuchi
Journal:  J Biol Chem       Date:  2001-12-13       Impact factor: 5.157

Review 2.  Wnt/beta-catenin signaling: components, mechanisms, and diseases.

Authors:  Bryan T MacDonald; Keiko Tamai; Xi He
Journal:  Dev Cell       Date:  2009-07       Impact factor: 12.270

3.  Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation.

Authors:  Tak-Heun Kim; Ju-Yeon Lee; Jin-A Baek; Jeong-Chae Lee; Xiao Yang; Makoto M Taketo; Rulang Jiang; Eui-Sic Cho
Journal:  Biochem Biophys Res Commun       Date:  2011-08-10       Impact factor: 3.575

4.  LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis.

Authors:  Dan-Ni Ren; Jinxiao Chen; Zhi Li; Hongwei Yan; Yan Yin; Da Wo; Jiankang Zhang; Luoquan Ao; Bo Chen; Takashi K Ito; Yihan Chen; Zhongmin Liu; Yongyong Li; Jianhua Yang; Xiaoling Lu; Yi Peng; Linghui Pan; Yongxiang Zhao; Shangfeng Liu; Weidong Zhu
Journal:  Nat Commun       Date:  2015-04-22       Impact factor: 14.919

Review 5.  Wnt regulation of planar cell polarity (PCP).

Authors:  Bo Gao
Journal:  Curr Top Dev Biol       Date:  2012       Impact factor: 4.897

6.  β-catenin is required in odontoblasts for tooth root formation.

Authors:  T H Kim; C H Bae; J C Lee; S O Ko; X Yang; R Jiang; E S Cho
Journal:  J Dent Res       Date:  2013-01-23       Impact factor: 6.116

7.  Wnt3a suppresses Wnt/β-catenin signaling and cancer cell proliferation following serum deprivation.

Authors:  Qingqing He; Hongwei Yan; Da Wo; Junjun Liu; Peng Liu; Jiankang Zhang; Limei Li; Bin Zhou; Jin Ge; Huashun Li; Shangfeng Liu; Weidong Zhu
Journal:  Exp Cell Res       Date:  2015-11-28       Impact factor: 3.905

8.  Spatiotemporal Expression of Wnt/β-catenin Signaling during Morphogenesis and Odontogenesis of Deciduous Molar in Miniature Pig.

Authors:  Xiaoshan Wu; Yan Li; Fu Wang; Lei Hu; Yang Li; Jinsong Wang; Chunmei Zhang; Songlin Wang
Journal:  Int J Biol Sci       Date:  2017-09-03       Impact factor: 6.580

9.  Transcriptome analysis of coding and long non-coding RNAs highlights the regulatory network of cascade initiation of permanent molars in miniature pigs.

Authors:  Fu Wang; Yang Li; Xiaoshan Wu; Min Yang; Wei Cong; Zhipeng Fan; Jinsong Wang; Chunmei Zhang; Jie Du; Songlin Wang
Journal:  BMC Genomics       Date:  2017-02-10       Impact factor: 3.969

10.  Ctbp2-mediated β-catenin regulation is required for exit from pluripotency.

Authors:  Tae Wan Kim; Sojung Kwak; Jihoon Shin; Byung-Hee Kang; Sang-Eun Lee; Min Young Suh; Jae-Hwan Kim; In-Young Hwang; Jong-Hyuk Lee; Jinmi Choi; Eun-Jung Cho; Hong-Duk Youn
Journal:  Exp Mol Med       Date:  2017-10-13       Impact factor: 8.718
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  3 in total

Review 1.  Kinase drug discovery 20 years after imatinib: progress and future directions.

Authors:  Philip Cohen; Darren Cross; Pasi A Jänne
Journal:  Nat Rev Drug Discov       Date:  2021-05-17       Impact factor: 112.288

2.  Bone morphogenetic protein 7 mediates stem cells migration and angiogenesis: therapeutic potential for endogenous pulp regeneration.

Authors:  Cheng Liang; Qingqing Liang; Xun Xu; Xiaojing Liu; Xin Gao; Maojiao Li; Jian Yang; Xiaotao Xing; Haisen Huang; Qi Tang; Li Liao; Weidong Tian
Journal:  Int J Oral Sci       Date:  2022-07-20       Impact factor: 24.897

Review 3.  Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?

Authors:  Juliana Baranova; Dominik Büchner; Werner Götz; Margit Schulze; Edda Tobiasch
Journal:  Int J Mol Sci       Date:  2020-06-04       Impact factor: 5.923
  3 in total

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