Enrico Cerrato1, Federico Giacobbe2, Cristina Rolfo3, Giorgio Quadri3, Francesco Tomassini3, Fabio Ferrari3, Fabio Mariani3, Matteo Anselmino2, Matteo Bianco4, Davide Belliggiano2, Luca Lo Savio5, Alfonso Franzé5, Umberto Barbero6, Italo Porto7, Hernán Mejía-Rentería8, Fernando Macaya8, Pablo Salinas9, Nieves Gonzalo8, Javier Escaned8, Laura Montagna4, Ferdinando Varbella3. 1. Interventional Cardiology Unit, Orbassano, and Infermi Hospital, San Luigi Gonzaga University Hospital, Rivoli, Turin, Italy. enrico.cerrato@gmail.com. 2. Division of Cardiology, "Città della Salute e della Scienza di Torino" Hospital, Department of Medical Sciences, University of Turin, Turin, Italy. 3. Interventional Cardiology Unit, Orbassano, and Infermi Hospital, San Luigi Gonzaga University Hospital, Rivoli, Turin, Italy. 4. Department of Cardiology, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy. 5. Cardiology Division, Infermi Hospital, Rivoli, Turin, Italy. 6. Cardiology Division, Santissima Annunziata Hospital, Savigliano, Italy. 7. Interventional Cardiology Unit, San Martino Hospital, University of Genoa, Genoa, Italy. 8. Hospital Clinico San Carlos IDISCC, Complutense University of Madrid, Madrid, Spain. 9. Servicio de Cardiologia, Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
Abstract
PURPOSE OF REVIEW: Spontaneous coronary artery dissection (SCAD) is a serious non-atherosclerotic disease, most frequently presenting as an acute coronary syndrome and affecting female patients. Considering that diagnosis of SCAD is often elusive, and its interventional treatment is associated to a higher rate of complications than obstructive atherosclerotic disease, we aim to review all the imaging tools currently available for the optimal diagnosis and treatment of this condition. RECENT FINDINGS: The developments in both invasive and non-invasive imaging alternatives to coronary angiography, such as intravascular ultrasound, optical coherence tomography, and computed coronary angiography, have largely contributed to appraise the epidemiology of SCAD, understand its causative pathophysiological mechanisms, and improve our ability to confirm doubtful cases of SCAD. Intracoronary imaging is also a valuable in deciding the best therapeutic approach and in guiding interventions in those patients requiring percutaneous treatment. Furthermore, non-invasive imaging is a key tool in ruling out significant extracoronary vascular abnormalities which frequently occur in patients with underlying conditions like fibromuscular dysplasia who develop SCAD. Main imaging tools employed in SCAD cases could have advantages and drawbacks. Focusing on different types of SCAD, operators should be able to choose the best imaging technique for diagnosis, management, and follow-up.
PURPOSE OF REVIEW: Spontaneous coronary artery dissection (SCAD) is a serious non-atherosclerotic disease, most frequently presenting as an acute coronary syndrome and affecting female patients. Considering that diagnosis of SCAD is often elusive, and its interventional treatment is associated to a higher rate of complications than obstructive atherosclerotic disease, we aim to review all the imaging tools currently available for the optimal diagnosis and treatment of this condition. RECENT FINDINGS: The developments in both invasive and non-invasive imaging alternatives to coronary angiography, such as intravascular ultrasound, optical coherence tomography, and computed coronary angiography, have largely contributed to appraise the epidemiology of SCAD, understand its causative pathophysiological mechanisms, and improve our ability to confirm doubtful cases of SCAD. Intracoronary imaging is also a valuable in deciding the best therapeutic approach and in guiding interventions in those patients requiring percutaneous treatment. Furthermore, non-invasive imaging is a key tool in ruling out significant extracoronary vascular abnormalities which frequently occur in patients with underlying conditions like fibromuscular dysplasia who develop SCAD. Main imaging tools employed in SCAD cases could have advantages and drawbacks. Focusing on different types of SCAD, operators should be able to choose the best imaging technique for diagnosis, management, and follow-up.
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