Madelon J H Metman1, Pim B Olthof2, Johannes B C van der Wal3, Thomas M van Gulik4, Daphne Roos3, Jan Willem T Dekker3. 1. Department of Surgery, Reinier de Graaf Gasthuis, Delft, the Netherlands. Electronic address: mmetman@gmail.com. 2. Department of Surgery, Reinier de Graaf Gasthuis, Delft, the Netherlands; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Surgery, Erasmus Medical Center, Rotterdam, the Netherlands. 3. Department of Surgery, Reinier de Graaf Gasthuis, Delft, the Netherlands. 4. Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Abstract
BACKGROUND: Gallbladder polyps are common incidental findings during abdominal ultrasonography. Cholecystectomy is recommended for polyps equal or greater than 10 mm on ultrasound due to their malignant potential. However, the majority of lesions appear to be pseudopolyps with no malignant potential. Our aim was to determine the correlation between ultrasonographic findings and histopathological findings after cholecystectomy for gallbladder polyps in two institutions. METHOD: A retrospective analysis was performed at two Dutch institutions of patients who underwent cholecystectomy. All cholecystectomies for suspected gallbladder polyps between January 2010 and August 2017 were included. Ultrasonographic and histopathological reports were analyzed. RESULTS: A total of 108 patients underwent cholecystectomy for gallbladder polyps. At abdominal ultrasound sixty-five patients (60.2%) were diagnosed with multiple gallbladder polyps. The mean diameter of the polyps was 11 mm. On pathological examination after cholecystectomy, only three specimens harbored true polyps. No anomalies were found in 48 (44%) patients and 51 (47%) had cholesterolosis. CONCLUSION: The prevalence of true gallbladder polyps was much lower in this study than reported in literature. After cholecystectomy for gallbladder polyps diagnosed by ultrasound, 97% of patients had non-neoplastic or not identifiable lesions in the gallbladder. These findings question the usefulness of current guidelines for management of suspected gallbladder polyps.
BACKGROUND:Gallbladder polyps are common incidental findings during abdominal ultrasonography. Cholecystectomy is recommended for polyps equal or greater than 10 mm on ultrasound due to their malignant potential. However, the majority of lesions appear to be pseudopolyps with no malignant potential. Our aim was to determine the correlation between ultrasonographic findings and histopathological findings after cholecystectomy for gallbladder polyps in two institutions. METHOD: A retrospective analysis was performed at two Dutch institutions of patients who underwent cholecystectomy. All cholecystectomies for suspected gallbladder polyps between January 2010 and August 2017 were included. Ultrasonographic and histopathological reports were analyzed. RESULTS: A total of 108 patients underwent cholecystectomy for gallbladder polyps. At abdominal ultrasound sixty-five patients (60.2%) were diagnosed with multiple gallbladder polyps. The mean diameter of the polyps was 11 mm. On pathological examination after cholecystectomy, only three specimens harbored true polyps. No anomalies were found in 48 (44%) patients and 51 (47%) had cholesterolosis. CONCLUSION: The prevalence of true gallbladder polyps was much lower in this study than reported in literature. After cholecystectomy for gallbladder polyps diagnosed by ultrasound, 97% of patients had non-neoplastic or not identifiable lesions in the gallbladder. These findings question the usefulness of current guidelines for management of suspected gallbladder polyps.
Authors: Orhun C Taskin; Olca Basturk; Michelle D Reid; Nevra Dursun; Pelin Bagci; Burcu Saka; Serdar Balci; Bahar Memis; Enrique Bellolio; Juan Carlos Araya; Juan Carlos Roa; Oscar Tapia; Hector Losada; Juan Sarmiento; Kee-Taek Jang; Jin-Young Jang; Burcin Pehlivanoglu; Mert Erkan; Volkan Adsay Journal: PLoS One Date: 2020-09-11 Impact factor: 3.240
Authors: Yonghua Shen; Jun Cao; Xiaoliang Zhou; Song Zhang; Juan Li; Guifang Xu; Xiaoping Zou; Ying Lu; Yuling Yao; Lei Wang Journal: Medicine (Baltimore) Date: 2020-10-23 Impact factor: 1.817