Literature DB >> 31479763

The plant hormone kinetin in disease therapy and healthy aging.

Alena Kadlecová1, Barbara Maková1, Marta Artal-Sanz2, Miroslav Strnad1, Jiří Voller3.   

Abstract

It has been more than 60 years since the discovery of kinetin, the first known member of a group of plant hormones called cytokinins. In this review we summarize the health-promoting activity of kinetin in animal systems, ranging from cells cultured in vitro through invertebrates to mammals. Kinetin has been shown to modulate aging, to delay age-related physiological decline and to protect against some neurodegenerative diseases. We also review studies on its mechanism of action, as well as point out gaps in our current knowledge.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Age-related diseases; Aging; Cytokinin; Kinetin

Mesh：

Substances：

Year:  2019        PMID： 31479763     DOI： 10.1016/j.arr.2019.100958

Source DB:  PubMed          Journal:  Ageing Res Rev        ISSN： 1568-1637            Impact factor:   10.895


  10 in total

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Review 2.  Trends and challenges in phytotherapy and phytocosmetics for skin aging.

Authors:  Idris Adewale Ahmed; Maryam Abimbola Mikail; Nor Hisam Zamakshshari; Mohd Rais Mustafa; Najihah Mohd Hashim; Rozana Othman
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3.  Cisplatin-Induced Reproductive Toxicity and Oxidative Stress: Ameliorative Effect of Kinetin.

Authors:  Rania Abdel-Latif; Moustafa Fathy; Hend Ali Anwar; Muhammad Naseem; Thomas Dandekar; Eman M Othman
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4.  Antiaging Effect of 4-N-Furfurylcytosine in Yeast Model Manifests through Enhancement of Mitochondrial Activity and ROS Reduction.

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Journal:  Antioxidants (Basel)       Date:  2022-04-26

5.  Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage.

Authors:  Juan Carlos Montesinos; Anas Abuzeineh; Aglaja Kopf; Alba Juanes-Garcia; Krisztina Ötvös; Jan Petrášek; Michael Sixt; Eva Benková
Journal:  EMBO J       Date:  2020-07-15       Impact factor: 11.598

6.  Modulatory and Toxicological Perspectives on the Effects of the Small Molecule Kinetin.

Authors:  Eman M Othman; Moustafa Fathy; Amany Abdlrehim Bekhit; Abdel-Razik H Abdel-Razik; Arshad Jamal; Yousef Nazzal; Shabana Shams; Thomas Dandekar; Muhammad Naseem
Journal:  Molecules       Date:  2021-01-28       Impact factor: 4.411

7.  Kinetin stimulates differentiation of C2C12 myoblasts.

Authors:  Michal Mielcarek; Mark Isalan
Journal:  PLoS One       Date:  2021-10-13       Impact factor: 3.240

Review 8.  Cytokinins: Wide-Spread Signaling Hormones from Plants to Humans with High Medical Potential.

Authors:  Moustafa Fathy; Sahar M Saad Eldin; Muhammad Naseem; Thomas Dandekar; Eman M Othman
Journal:  Nutrients       Date:  2022-04-02       Impact factor: 5.717

9.  Kinetin Ameliorates Cisplatin-Induced Hepatotoxicity and Lymphotoxicity via Attenuating Oxidative Damage, Cell Apoptosis and Inflammation in Rats.

Authors:  Moustafa Fathy; Mostafa A Darwish; Al-Shaimaa M Abdelhamid; Gehad M Alrashedy; Othman Ali Othman; Muhammad Naseem; Thomas Dandekar; Eman M Othman
Journal:  Biomedicines       Date:  2022-07-06

10.  Integrated structural and functional analysis of the protective effects of kinetin against oxidative stress in mammalian cellular systems.

Authors:  Muhammad Naseem; Eman M Othman; Moustafa Fathy; Jibran Iqbal; Fares M Howari; Fatima A AlRemeithi; Geema Kodandaraman; Helga Stopper; Elena Bencurova; Dimitrios Vlachakis; Thomas Dandekar
Journal:  Sci Rep       Date:  2020-08-07       Impact factor: 4.379
  10 in total

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