Literature DB >> 3147796

The role of cachectin/TNF in the pathogenesis of tuberculosis.

C L Silva1, L H Faccioli, G M Rocha.   

Abstract

The presence of cachectin or tumor necrosis factor (TNF) associated with hypertriglyceridemia was demonstrated in the serum of patients with pulmonary tuberculosis. The hyperlipidemia that accompanies this infection may be mediated by the TNF inhibition of lipoprotein lipase activity. This sequence of events may be sufficient to explain, in part, the complex metabolic changes and emaciation observed in tuberculosis patients.

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Year:  1988        PMID: 3147796

Source DB:  PubMed          Journal:  Braz J Med Biol Res        ISSN: 0100-879X            Impact factor:   2.590


  9 in total

1.  Tumor necrosis factor alpha in children with sickle cell disease in stable condition.

Authors:  S Kuvibidila; R Gardner; D Ode; L Yu; G Lane; R P Warrier
Journal:  J Natl Med Assoc       Date:  1997-09       Impact factor: 1.798

2.  Association between increased levels of TNF-alpha, decreased levels of prealbumin and retinol-binding protein, and disease outcome.

Authors:  S Kuvibidila; L Yu; R Gardner; M Velez; D Ode; R P Warrier
Journal:  J Natl Med Assoc       Date:  2000-10       Impact factor: 1.798

3.  Tumor necrosis factor (cachectin) mediates induction of cachexia by cord factor from mycobacteria.

Authors:  C L Silva; L H Faccioli
Journal:  Infect Immun       Date:  1988-12       Impact factor: 3.441

Review 4.  Adventures within the speckled band: heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma.

Authors:  Molly A Matty; Francisco J Roca; Mark R Cronan; David M Tobin
Journal:  Immunol Rev       Date:  2015-03       Impact factor: 12.988

5.  Mechanisms of stimulation of interleukin-1 beta and tumor necrosis factor-alpha by Mycobacterium tuberculosis components.

Authors:  Y Zhang; M Doerfler; T C Lee; B Guillemin; W N Rom
Journal:  J Clin Invest       Date:  1993-05       Impact factor: 14.808

6.  Tumour necrosis factor production in vivo and in vitro in response to Paracoccidioides brasiliensis and the cell wall fractions thereof.

Authors:  F Figueiredo; L M Alves; C L Silva
Journal:  Clin Exp Immunol       Date:  1993-08       Impact factor: 4.330

7.  Parallel antitumor, granuloma-forming and tumor-necrosis-factor-priming activities of mycoloyl glycolipids from Nocardia rubra that differ in carbohydrate moiety: structure-activity relationships.

Authors:  Y Natsuhara; S Oka; K Kaneda; Y Kato; I Yano
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

8.  Tumor necrosis factor and macrophage activation are important in clearance of Nocardia brasiliensis from the livers and spleens of mice.

Authors:  C L Silva; L H Faccioli
Journal:  Infect Immun       Date:  1992-09       Impact factor: 3.441

9.  Modulation of murine hepatic lipase activity by exogenous and endogenous Kupffer-cell activation.

Authors:  D B Magilavy; R Zhan; D D Black
Journal:  Biochem J       Date:  1993-05-15       Impact factor: 3.857

  9 in total

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