Literature DB >> 3147717

A possible physiological function of pancreatic pro-colipase activation peptide in appetite regulation.

C Erlanson-Albertsson1, A Larsson.   

Abstract

Pancreatic pro-colipase activation peptide, a pentapeptide with the sequence VPDPR was found to significantly suppress food intake of 20 h fasted Sprague-Dawley rats in a dose-dependent way. A rat treated with pro-colipase-enriched pellets for 26 days showed decreased daily food intake and retarded growth, which were restored during a following period of regular feeding. Genetically obese Zucker rats (fa/fa) were found to contain a reduced content of pancreatic pro-colipase (60% reduction), whereas the pancreatic lipase content was normal. A physiological function of pancreatic pro-colipase activation peptide as an endogenous satiety signal is suggested.

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Year:  1988        PMID： 3147717     DOI： 10.1016/0300-9084(88)90191-5

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  7 in total

1.  Enterostatin inhibits insulin secretion from isolated perifused rat islets.

Authors:  C Erlanson-Albertsson; B Hering; R G Bretzel; K Federlin
Journal:  Acta Diabetol       Date:  1994-09       Impact factor: 4.280

2.  Procolipase mRNA: tissue localization and effects of diet and adrenalectomy.

Authors:  S Okada; D A York; G A Bray
Journal:  Biochem J       Date:  1993-06-15       Impact factor: 3.857

3.  Nutritive, Post-ingestive Signals Are the Primary Regulators of AgRP Neuron Activity.

Authors:  Zhenwei Su; Amber L Alhadeff; J Nicholas Betley
Journal:  Cell Rep       Date:  2017-12-05       Impact factor: 9.423

4.  Enterostatin deficiency increases serum cholesterol but does not influence growth and food intake in mice.

Authors:  Rita Miller; Dymphna D'Agostino; Charlotte Erlanson-Albertsson; Mark E Lowe
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-07-21       Impact factor: 4.310

Review 5.  Development and regulation of porcine pancreatic function.

Authors:  S G Pierzynowski; B R Weström; J Svendsen; L Svendsen; B W Karlsson
Journal:  Int J Pancreatol       Date:  1995-10

6.  Effect of a satiating meal on the concentrations of procolipase propeptide in the serum and urine of normal and morbidly obese subjects.

Authors:  R C Bowyer; W M Rowston; A M Jehanli; J H Lacey; J Hermon-Taylor
Journal:  Gut       Date:  1993-11       Impact factor: 23.059

7.  Crystallographic study of the structure of colipase and of the interaction with pancreatic lipase.

Authors:  M P Egloff; L Sarda; R Verger; C Cambillau; H van Tilbeurgh
Journal:  Protein Sci       Date:  1995-01       Impact factor: 6.725
  7 in total

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