Literature DB >> 31476175

Acute flaccid myelitis: Rehabilitation challenges and outcomes in a pediatric cohort.

Michelle E Melicosta1,2, Janet Dean3, Kaitlin Hagen4, Kathleen Oppenheimer4, Courtney Porter3, Suzanne Rybczynski1,2, Cynthia Salorio1, Cristina Sadowsky3.   

Abstract

PURPOSE: To describe one institution's experience in the rehabilitation of children with acute flaccid myelitis (AFM). This study reviews the medical and rehabilitative course and functional outcomes of a cohort of children who underwent Activity Based Restorative Therapy (ABRT) at a single center.
METHODS: Children with AFM presenting for rehabilitation between March 2005 and January 2017 were identified and a retrospective chart review was conducted. Changes in medical and functional status were assessed using multiple standardized instruments, as well as a chart review of medical progress.
RESULTS: Thirty-one children with AFM treated at our institution in the study time period were identified. Of these, seventeen received inpatient treatment, and fourteen received solely outpatient interventions. Their medical and functional outcomes are described with use of standardized measures when available.
CONCLUSIONS: Children with flaccid paralysis due to AFM undergoing structured, comprehensive rehabilitation interventions, even when these are initiated long after paralysis onset, can make significant neurologic and functional gains. Recovery of function and prevention of comorbidities are the main therapeutic targets for interventions in this population.

Entities:  

Keywords:  Acute flaccid myelitis; paralysis; rehabilitation functional outcomes; spinal cord injury

Mesh:

Year:  2019        PMID: 31476175     DOI: 10.3233/PRM-180549

Source DB:  PubMed          Journal:  J Pediatr Rehabil Med        ISSN: 1874-5393


  6 in total

1.  A Systematic Review of the Scientific Literature for Rehabilitation/Habilitation Among Individuals With Pediatric-Onset Spinal Cord Injury.

Authors:  Amanda McIntyre; Cristina Sadowsky; Andrea Behrman; Rebecca Martin; Marika Augutis; Caitlin Cassidy; Randal Betz; Per Ertzgaard; M J Mulcahey
Journal:  Top Spinal Cord Inj Rehabil       Date:  2022-04-12

2.  Scoliosis in Pediatric Patients With Acute Flaccid Myelitis.

Authors:  Krishna V Suresh; Alexander Karius; Kevin Y Wang; Cristina Sadowsky; Paul D Sponseller
Journal:  Top Spinal Cord Inj Rehabil       Date:  2021-08-23

3.  Improvements in Function Following Inpatient Activity-Based Therapy for Children With Acute Flaccid Myelitis.

Authors:  Kaitlin Hagen; Courtney Porter; Rebecca Martin; Janet Dean; Cynthia Salorio; Cristina Sadowsky
Journal:  Top Spinal Cord Inj Rehabil       Date:  2021-01-20

Review 4.  Acute flaccid myelitis: cause, diagnosis, and management.

Authors:  Olwen C Murphy; Kevin Messacar; Leslie Benson; Riley Bove; Jessica L Carpenter; Thomas Crawford; Janet Dean; Roberta DeBiasi; Jay Desai; Matthew J Elrick; Raquel Farias-Moeller; Grace Y Gombolay; Benjamin Greenberg; Matthew Harmelink; Sue Hong; Sarah E Hopkins; Joyce Oleszek; Catherine Otten; Cristina L Sadowsky; Teri L Schreiner; Kiran T Thakur; Keith Van Haren; Carolina M Carballo; Pin Fee Chong; Amary Fall; Vykuntaraju K Gowda; Jelte Helfferich; Ryutaro Kira; Ming Lim; Eduardo L Lopez; Elizabeth M Wells; E Ann Yeh; Carlos A Pardo
Journal:  Lancet       Date:  2020-12-23       Impact factor: 79.321

Review 5.  Enterovirus D68 molecular and cellular biology and pathogenesis.

Authors:  Matthew J Elrick; Andrew Pekosz; Priya Duggal
Journal:  J Biol Chem       Date:  2021-01-21       Impact factor: 5.157

6.  Acute Flaccid Myelitis: A Call for Vigilance and an Update on Management.

Authors:  Sarah E Hopkins; Jay Desai; Leslie Benson
Journal:  Pediatr Neurol       Date:  2020-09-10       Impact factor: 3.372

  6 in total

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