Literature DB >> 31475995

A visible-light photoactivatable di-nuclear PtIV triazolato azido complex.

Kezi Yao1, Arnau Bertran, Alison Howarth, Jose M Goicoechea, Samuel M Hare, Nicholas H Rees, Mohammadali Foroozandeh, Alice M Bowen, Nicola J Farrer.   

Abstract

A novel PtIV triazolato azido complex [3]-[N1,N3] has been synthesised via a strain-promoted double-click reaction (SPDC) between a PtIV azido complex (1) and the Sondheimer diyne (2). Photoactivation of [3]-[N1,N3] with visible light (452 nm) in the presence of 5'-guanosine monophosphate (5'-GMP) produced both PtIV and PtII 5'-GMP species; EPR spectroscopy confirmed the production of both azidyl and hydroxyl radicals. Spin-trapping of photogenerated radicals - particularly hydroxyl radicals - was significantly reduced in the presence of 5'-GMP.

Entities:  

Year:  2019        PMID： 31475995      PMCID： PMC6984334          DOI： 10.1039/c9cc05310g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  31 in total

1.  Double elimination protocol for synthesis of 5,6,11,12-tetradehydrodibenzo[a,e]cyclooctene.

Authors:  Akihiro Orita; Daiki Hasegawa; Takehiko Nakano; Junzo Otera
Journal:  Chemistry       Date:  2002-05-03       Impact factor: 5.236

2.  Precision glycocalyx editing as a strategy for cancer immunotherapy.

Authors:  Han Xiao; Elliot C Woods; Petar Vukojicic; Carolyn R Bertozzi
Journal:  Proc Natl Acad Sci U S A       Date:  2016-08-22       Impact factor: 11.205

Review 3.  Medicinal attributes of 1,2,3-triazoles: Current developments.

Authors:  Divya Dheer; Virender Singh; Ravi Shankar
Journal:  Bioorg Chem       Date:  2017-01-18       Impact factor: 5.275

Review 4.  Cu-free click cycloaddition reactions in chemical biology.

Authors:  John C Jewett; Carolyn R Bertozzi
Journal:  Chem Soc Rev       Date:  2010-04       Impact factor: 54.564

5.  Beyond click chemistry - supramolecular interactions of 1,2,3-triazoles.

Authors:  Benjamin Schulze; Ulrich S Schubert
Journal:  Chem Soc Rev       Date:  2014-02-03       Impact factor: 54.564

Review 6.  The 1,2,3-triazole ring as a bioisostere in medicinal chemistry.

Authors:  Elisa Bonandi; Michael S Christodoulou; Gaia Fumagalli; Dario Perdicchia; Giulio Rastelli; Daniele Passarella
Journal:  Drug Discov Today       Date:  2017-07-01       Impact factor: 7.851

7.  Development of an Efficient Dual-Action GST-Inhibiting Anticancer Platinum(IV) Prodrug.

Authors:  Keefe Guang Zhi Lee; Maria V Babak; Andrea Weiss; Paul J Dyson; Patrycja Nowak-Sliwinska; Diego Montagner; Wee Han Ang
Journal:  ChemMedChem       Date:  2018-05-28       Impact factor: 3.466

8.  Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells.

Authors:  Henning Stöckmann; André A Neves; Shaun Stairs; Heather Ireland-Zecchini; Kevin M Brindle; Finian J Leeper
Journal:  Chem Sci       Date:  2011-05       Impact factor: 9.825

9.  A novel Pt(iv) mono azido mono triazolato complex evolves azidyl radicals following irradiation with visible light.

Authors:  Kezi Yao; Arnau Bertran; Jacques Morgan; Samuel M Hare; Nicholas H Rees; Alan M Kenwright; Katharina Edkins; Alice M Bowen; Nicola J Farrer
Journal:  Dalton Trans       Date:  2019-05-15       Impact factor: 4.390

10.  Platinum(iv) azido complexes undergo copper-free click reactions with alkynes.

Authors:  Nicola J Farrer; Gitanjali Sharma; Rachel Sayers; Evyenia Shaili; Peter J Sadler
Journal:  Dalton Trans       Date:  2018-08-07       Impact factor: 4.390
View more
  3 in total

1.  Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors:  Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal:  Chem Rev       Date:  2020-10-30       Impact factor: 60.622

2.  Solvent-Dependent Reactivity and Photochemistry of Dinuclear and Mononuclear Platinum(IV) Azido Triazaolato Complexes.

Authors:  Kezi Yao; Arnau Bertran; Jacques Morgan; Charlotte Greenhalgh; Katharina Edkins; Alice M Bowen; Nicola J Farrer
Journal:  Eur J Inorg Chem       Date:  2021-03-16       Impact factor: 2.524

Review 3.  Exploiting azide-alkyne click chemistry in the synthesis, tracking and targeting of platinum anticancer complexes.

Authors:  Nicola J Farrer; Darren M Griffith
Journal:  Curr Opin Chem Biol       Date:  2020-01-13       Impact factor: 8.822
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.