| Literature DB >> 31474357 |
Wan-Chen Cheng1, Ping-Chih Ho2.
Abstract
Elucidating how tumor-intrinsic pathways regulate T cell infiltration in tumors is crucial for developing new therapeutic strategies for immune checkpoint blockade therapy. Here, we review recent progress on how these pathways orchestrate immune status in tumors and discuss the potential interventions for reprogramming the tumor microenvironment for cancer treatment.Entities:
Keywords: antitumor immune cycle; conventional type I dendritic cells; immune checkpoint blockade; resistance; tumor microenvironment
Year: 2019 PMID： 31474357 DOI： 10.1016/j.trecan.2019.06.005
Source DB: PubMed Journal: Trends Cancer ISSN： 2405-8025