Faisal Nooh1,2,3, Lisa Crump4,5, Abdiwahab Hashi6, Rea Tschopp4,5,7, Esther Schelling4,5, Klaus Reither4,5, Jan Hattendorf4,5, Seid M Ali4,5,6, Brigit Obrist4,5, Jürg Utzinger4,5, Jakob Zinsstag4,5. 1. Swiss Tropical and Public Health Institute, P.O. Box, CH-4002, Basel, Switzerland. faisalnooh.ali@swisstph.ch. 2. University of Basel, P.O. Box, CH-4003, Basel, Switzerland. faisalnooh.ali@swisstph.ch. 3. Jigjiga University, P.O. Box, 1020, Jigjiga, Ethiopia. faisalnooh.ali@swisstph.ch. 4. Swiss Tropical and Public Health Institute, P.O. Box, CH-4002, Basel, Switzerland. 5. University of Basel, P.O. Box, CH-4003, Basel, Switzerland. 6. Jigjiga University, P.O. Box, 1020, Jigjiga, Ethiopia. 7. Armauer Hansen Research Institute, P.O. Box, 1005, Addis Ababa, Ethiopia.
Abstract
BACKGROUND: Directly observed treatment, short-course (DOTS) is the current mainstay to control tuberculosis (TB) worldwide. Context-specific adaptations of DOTS have impending implications in the fight against TB. In Ethiopia, there is a national TB control programme with the goal to eliminate TB, but uneven distribution across lifestyle gradients remains a challenge. Notably, the mobile pastoralist communities in the country are disproportionately left uncovered. The aim of this study was to summarize the evidence base from published literature to guide TB control strategy for mobile pastoralist communities in Ethiopia. MAIN TEXT: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and systematically reviewed articles in seven electronic databases: Excerptra Medical Database, African Journal Online, PubMed, Google Scholar, Centre for Agriculture and Bioscience International Direct, Cochrane Library and Web of Science. The databases were searched from inception to December 31, 2018, with no language restriction. We screened 692 items of which 19 met our inclusion criteria. Using a meta-ethnographic method, we identified six themes: (i) pastoralism in Ethiopia; (ii) pastoralists' livelihood profile; (iii) pastoralists' service utilisation; (iv) pastoralists' knowledge and awareness on TB control services; (v) challenges of TB control in pastoral settings; and (vi) equity disparities affecting pastoralists. Our interpretation triangulates the results across all included studies and shows that TB control activities observed in pastoralist regions of Ethiopia are far fewer than elsewhere in the country. CONCLUSIONS: This systematic review and meta-synthesis shows that TB control in Ethiopia does not align well with the pastoralist lifestyle. Inaccessibility and lack of acceptability of TB care are the key bottlenecks to pastoralist TB service provision. Targeting these two parameters holds promise to enhance effectiveness of an intervention.
BACKGROUND: Directly observed treatment, short-course (DOTS) is the current mainstay to control tuberculosis (TB) worldwide. Context-specific adaptations of DOTS have impending implications in the fight against TB. In Ethiopia, there is a national TB control programme with the goal to eliminate TB, but uneven distribution across lifestyle gradients remains a challenge. Notably, the mobile pastoralist communities in the country are disproportionately left uncovered. The aim of this study was to summarize the evidence base from published literature to guide TB control strategy for mobile pastoralist communities in Ethiopia. MAIN TEXT: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and systematically reviewed articles in seven electronic databases: Excerptra Medical Database, African Journal Online, PubMed, Google Scholar, Centre for Agriculture and Bioscience International Direct, Cochrane Library and Web of Science. The databases were searched from inception to December 31, 2018, with no language restriction. We screened 692 items of which 19 met our inclusion criteria. Using a meta-ethnographic method, we identified six themes: (i) pastoralism in Ethiopia; (ii) pastoralists' livelihood profile; (iii) pastoralists' service utilisation; (iv) pastoralists' knowledge and awareness on TB control services; (v) challenges of TB control in pastoral settings; and (vi) equity disparities affecting pastoralists. Our interpretation triangulates the results across all included studies and shows that TB control activities observed in pastoralist regions of Ethiopia are far fewer than elsewhere in the country. CONCLUSIONS: This systematic review and meta-synthesis shows that TB control in Ethiopia does not align well with the pastoralist lifestyle. Inaccessibility and lack of acceptability of TB care are the key bottlenecks to pastoralist TB service provision. Targeting these two parameters holds promise to enhance effectiveness of an intervention.
Authors: Brigit Obrist; Nelly Iteba; Christian Lengeler; Ahmed Makemba; Christopher Mshana; Rose Nathan; Sandra Alba; Angel Dillip; Manuel W Hetzel; Iddy Mayumana; Alexander Schulze; Hassan Mshinda Journal: PLoS Med Date: 2007-10 Impact factor: 11.069