Literature DB >> 31474042

[Clinical effects of artificial dermis combined with vacuum sealing drainage and autologous split-thickness skin graft in repair of scar contracture deformity after extensive burn].

S Chen1, L W Zheng, W Liu, Z H Chen.   

Abstract

Objective: To explore the clinical effects of artificial dermis combined with vacuum sealing drainage (VSD) and autologous split-thickness skin graft in repair of scar contracture deformity after extensive burn.
Methods: A total of 8 patients with scar hyperplasia and contracture deformity on joint after healing of extensive burn were admitted to our hospital from August 2015 to August 2017. There were 5 females and 3 males aged 8 to 45 years with an average of 23 years. In the first stage operation, scar tissue on contracture site was removed, and the wound was covered by artificial dermis followed by continued VSD treatment. On 10-14 d after the first stage operation, the artificial dermis tissue formed, and the second stage autologous split-thickness skin grafting and continued VSD treatment were performed. Routine anti-scar therapy was carried out after healing of wounds. Time of wound healing after the second stage operation was recorded. Colour and texture of the split-thickness skin graft, scar formation condition of the donor site, and action condition of the operation site during follow-up were observed.
Results: The wounds of 8 patients were healed in 10-14 d after the second stage operation. During follow-up of 6-24 months, the split-thickness skin graft was with smooth surface and good elasticity, and the function of joint recovered well. The donor site in head healed well with no scar. Only pigmentation was left in the donor site of thigh, and scar was not obvious. The patients and their family members were satisfied. Conclusions: After application of artificial dermis combined with VSD and autologous split-thickness skin graft in repair of scar contracture deformity after extensive burn, the skin grafting area and donor site were with unobvious scar hyperplasia, and the joint function in the operation area was good.

Entities:  

Keywords:  Artificial dermis; Burns; Cicatrix; Negative-pressure wound therapy; Skin transplantation

Mesh:

Year:  2019        PMID: 31474042     DOI: 10.3760/cma.j.issn.1009-2587.2019.08.010

Source DB:  PubMed          Journal:  Zhonghua Shao Shang Za Zhi        ISSN: 1009-2587


  2 in total

1.  The efficacy of artificial dermis combined with continuous vacuum sealing drainage in deep neck multiple spaces infection treatment.

Authors:  Xiang Gu; Wei Chen; Kun Yuan; Jian Tan; Suguang Sun
Journal:  Medicine (Baltimore)       Date:  2021-02-05       Impact factor: 1.817

2.  Comparison of therapeutic effects between artificial dermis combined with autologous split-thickness skin grafting and autologous intermediate-thickness skin grafting alone in severely burned patients: A prospective randomised study.

Authors:  Feng Shang; Yan-Hua Lu; Jian Gao; Qiang Hou
Journal:  Int Wound J       Date:  2020-10-30       Impact factor: 3.315

  2 in total

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