Literature DB >> 31473697

Clinical and Microbiological Investigation of the Effects of Probiotics Combined with Scaling and Root Planing in the Management of Chronic Periodontitis: A Randomized, Controlled Study.

Preet Kanwal Dhaliwal1, Vishakha Grover2, Ranjan Malhotra3, Anoop Kapoor4.   

Abstract

AIM: To assess the adjunctive effect of probiotics to scaling and root planing in the management of chronic periodontitis.
MATERIALS AND METHODS: Thirty systemically healthy subjects in the age range of 20 - 55 years suffering from chronic generalized periodontitis were selected and randomly assigned to a control group of patients who received scaling and root planing (SRP) alone, or a test group of patients who received SRP supplemented with probiotic administration, i.e., Bifilac lozenges. The following baseline clinical parameters were recorded at selected teeth: plaque index, gingival index, probing pocket depth and relative attachment level. Microbiological counts of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia were assessed in pooled subgingival plaque samples. The parameters were recorded again at 30 days, 45 days and 3 months from baseline.
RESULTS: Statistically significant reductions were observed for plaque index, gingival index, and probing pocket depth, and a significant gain in relative attachment level in both groups. Microbiological analysis showed significant reduction for P. gingivalis at all recall intervals in the test group compared to controls. The intergroup comparison for differences in mean counts of P. gingivalis was found to be significant for the test group at 3 months (p = 0.028).
CONCLUSION: Probiotics can be considered as a potentially safe and effective adjunct to scaling and root planing in the management of chronic periodontitis.

Entities:  

Keywords:  A. actinomycetemcomitans; Bifilac lozenges; P. gingivalis; P. intermedia; chronic periodontitis; probiotics; scaling and root planing

Year:  2017        PMID: 31473697

Source DB:  PubMed          Journal:  J Int Acad Periodontol        ISSN: 1466-2094


  4 in total

Review 1.  The Use of Probiotics as Adjuvant Therapy of Periodontal Treatment: A Systematic Review and Meta-Analysis of Clinical Trials.

Authors:  Louis Hardan; Rim Bourgi; Carlos Enrique Cuevas-Suárez; Maythé Flores-Rodríguez; Arianna Omaña-Covarrubias; Marco Nicastro; Florin Lazarescu; Maciej Zarow; Paulo Monteiro; Natalia Jakubowicz; Patrycja Proc; Monika Lukomska-Szymanska
Journal:  Pharmaceutics       Date:  2022-05-09       Impact factor: 6.525

Review 2.  The Clinical, Microbiological, and Immunological Effects of Probiotic Supplementation on Prevention and Treatment of Periodontal Diseases: A Systematic Review and Meta-Analysis.

Authors:  Zohre Gheisary; Razi Mahmood; Aparna Harri Shivanantham; Juxin Liu; Jessica R L Lieffers; Petros Papagerakis; Silvana Papagerakis
Journal:  Nutrients       Date:  2022-02-28       Impact factor: 5.717

3.  Comparative Evaluation of Gingival Crevicular Fluid Interleukin-17, 18 and 21 in Different Stages of Periodontal Health and Disease.

Authors:  Vineet Nair; Vishakha Grover; Suraj Arora; Gotam Das; Irfan Ahmad; Anchal Ohri; Shan Sainudeen; Priyanka Saluja; Arindam Saha
Journal:  Medicina (Kaunas)       Date:  2022-08-03       Impact factor: 2.948

Review 4.  Classic vs. Novel Antibacterial Approaches for Eradicating Dental Biofilm as Adjunct to Periodontal Debridement: An Evidence-Based Overview.

Authors:  Ali Abdulkareem; Hayder Abdulbaqi; Sarhang Gul; Mike Milward; Nibras Chasib; Raghad Alhashimi
Journal:  Antibiotics (Basel)       Date:  2021-12-22
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.