Literature DB >> 31472146

Chrysin: Pharmacological and therapeutic properties.

Saima Naz1, Muhammad Imran2, Abdur Rauf3, Ilkay Erdogan Orhan4, Mohammad Ali Shariati5, Muhammad Shahbaz6, Tahira Batool Qaisrani6, Zafar Ali Shah7, Sergey Plygun8, Mojtaba Heydari9.   

Abstract

Chrysin is a promising phytochemical that is categorized under the class of flavonoids based on its chemical structure. Naturally, it is widely present in propolis, honey, passion fruit, and even in mushrooms and other plant sources, whereas its synthetic counterparts are also being employed for pharmacological purposes. It has widely been employed in treatment of various degenerative disorders and provides cytotoxic and anti-inflammatory functions. Its antioxidant and disease preventing abilities are attributed to its structural diversity arising in ring-A and absence of oxygenation in B and C ring. In this review, the scientific studies are being reported emphasizing benefits and its allied health claims on chrysin in numerous metabolic malfunctions.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Anti-inflammatory; Antioxidant; Chrysin; Cytotoxic; Flavonoids; Health claims

Mesh:

Substances:

Year:  2019        PMID: 31472146     DOI: 10.1016/j.lfs.2019.116797

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  26 in total

1.  Glycolytic inhibition: an effective strategy for developing calorie restriction mimetics.

Authors:  Donald K Ingram; George S Roth
Journal:  Geroscience       Date:  2020-11-12       Impact factor: 7.713

Review 2.  A focus on natural products for preventing and cure of mitochondrial dysfunction in Parkinson's disease.

Authors:  Abbas Mohammadipour
Journal:  Metab Brain Dis       Date:  2022-02-14       Impact factor: 3.584

3.  Chrysin protects cardiac H9c2 cells against H2O2-induced endoplasmic reticulum stress by up-regulating the Nrf2/PERK pathway.

Authors:  Subramani Yuvaraj; Arumugam Kalaiselvi Ajeeth; Shanavas Syed Mohamed Puhari; Albert Abhishek; Tharmarajan Ramprasath; Varadaraj Vasudevan; Narasimman Vignesh; Govindan Sadasivam Selvam
Journal:  Mol Cell Biochem       Date:  2022-08-09       Impact factor: 3.842

4.  [Mechanism of PI3K/AKT/mTOR signaling pathway for mediating anti-inflammatory and anti-oxidant effects of chrysin: a protein microarray-based study].

Authors:  S Cai; Q Li; H Zhou; Y Xu; J Song; C Gan; Z Qi; S Qi
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2021-10-20

5.  The effects of chrysin and naringin on cyclophosphamide-induced erythrocyte damage in rats: biochemical evaluation of some enzyme activities in vivo and in vitro.

Authors:  Yusuf Temel; Cüneyt Çağlayan; Barzan Mirza Ahmed; Fatih Mehmet Kandemir; Mehmet Çiftci
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2020-10-26       Impact factor: 3.000

Review 6.  Thioredoxin-interacting protein (TXNIP) as a target for Alzheimer's disease: flavonoids and phenols.

Authors:  Meng Zhang; Guanhua Hu; Nan Shao; Yunpeng Qin; Qian Chen; Yan Wang; Peng Zhou; Biao Cai
Journal:  Inflammopharmacology       Date:  2021-08-04       Impact factor: 4.473

7.  Sweet Cherry Byproducts Processed by Green Extraction Techniques as a Source of Bioactive Compounds with Antiaging Properties.

Authors:  Luz Agulló-Chazarra; Isabel Borrás-Linares; Jesús Lozano-Sánchez; Antonio Segura-Carretero; Vicente Micol; María Herranz-López; Enrique Barrajón-Catalán
Journal:  Antioxidants (Basel)       Date:  2020-05-13

8.  Antibacterial Activity of Some Flavonoids and Organic Acids Widely Distributed in Plants.

Authors:  Artur Adamczak; Marcin Ożarowski; Tomasz M Karpiński
Journal:  J Clin Med       Date:  2019-12-31       Impact factor: 4.241

Review 9.  Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives.

Authors:  Ebrahim Rahmani Moghadam; Hui Li Ang; Sholeh Etehad Asnaf; Amirhossein Zabolian; Hossein Saleki; Mohammad Yavari; Hossein Esmaeili; Ali Zarrabi; Milad Ashrafizadeh; Alan Prem Kumar
Journal:  Biomolecules       Date:  2020-09-27

10.  Chrysin Induced Cell Apoptosis Through H19/let-7a/COPB2 Axis in Gastric Cancer Cells and Inhibited Tumor Growth.

Authors:  Lin Chen; Qirong Li; Ziping Jiang; Chengshun Li; Haobo Hu; Tiedong Wang; Yan Gao; Dongxu Wang
Journal:  Front Oncol       Date:  2021-06-03       Impact factor: 6.244

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