Giuliano Reboa1, Marco Gipponi2, Piero Fregatti3,4, Francesca Depaoli5. 1. Department of Surgery, Coloproctology Unit - Casa di Cura San Camillo, Forte dei Marmi (Lucca), Italy. 2. Breast Surgery Clinic, Osp. Policlinico San Martino, Genoa, Italy marco.gipponi@hsanmartino.it. 3. Breast Surgery Clinic, Osp. Policlinico San Martino, Genoa, Italy. 4. School of Medicine, University of Genoa, Genoa, Italy. 5. Breast Surgery Unit, Azienda Sanitaria Locale 3, Genoa, Italy.
Abstract
BACKGROUND/AIM: This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms. PATIENTS AND METHODS: Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested). RESULTS: "Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0. CONCLUSION: The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks. Copyright
BACKGROUND/AIM: This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms. PATIENTS AND METHODS: Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested). RESULTS: "Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0. CONCLUSION: The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks. Copyright
Authors: P Boccasanta; P G Capretti; M Venturi; U Cioffi; M De Simone; G Salamina; E Contessini-Avesani; A Peracchia Journal: Am J Surg Date: 2001-07 Impact factor: 2.565
Authors: Giuliano Reboa; Marco Gipponi; Maurizio Gallo; Giovanni Ciotta; Marco Tarantello; Angelo Caviglia; Antonio Pagliazzo; Luigi Masoni; Giuseppe Caldarelli; Fabio Gaj; Bruno Masci; Andrea Verdi Journal: Surg Res Pract Date: 2016-02-21