Literature DB >> 3146973

The conjugation of 4-nitroquinoline 1-oxide, a potent carcinogen, by mammalian glutathione transferases. 4-Nitroquinoline 1-oxide conjugation by human, rat and mouse liver cytosols, extrahepatic organs of mice and purified mouse glutathione transferase isoenzymes.

J S Stanley1, A M Benson.   

Abstract

The conjugation of 4-nitroquinoline 1-oxide with GSH by human, rat and mouse liver cytosols, by purified mouse GSH transferases and by extrahepatic organ cytosols of male and female mice was investigated. 4-Nitroquinoline 1-oxide was as effectively conjugated by human liver cytosol as was 1-chloro-2,4-dinitrobenzene, at a substrate concentration of 0.1 mM. Mouse isoenzymes composed of Yb1 and Yf subunits exhibited high activity towards 4-nitroquinoline 1-oxide. Human, rat and mouse hepatic activities towards this substrate correlated with the hepatic isoenzyme compositions.

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Year:  1988        PMID： 3146973      PMCID： PMC1135404          DOI： 10.1042/bj2560303

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  19 in total

1.  Multiple forms of human glutathione S-transferase and their affinity for bilirubin.

Authors:  K Kamisaka; W H Habig; J N Ketley; M Arias; W B Jakoby
Journal:  Eur J Biochem       Date:  1975-12-01

2.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

Review 3.  The glutathione S-transferases: a group of multifunctional detoxification proteins.

Authors:  W B Jakoby
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1978

4.  The metabolism of 4-nitroquinoline-1-oxide, a carcinogen. 3. An enzyme catalyzing the conversion of 4-nitroquinoline-1-oxide to 4-hydroxyaminoquinoline-1-oxide in rat liver and hepatomas.

Authors:  T Sugimura; K Okabe; M Nagao
Journal:  Cancer Res       Date:  1966-08       Impact factor: 12.701

Review 5.  The role of nonenzymatic reactions of glutathione in xenobiotic metabolism.

Authors:  B Ketterer
Journal:  Drug Metab Rev       Date:  1982       Impact factor: 4.518

6.  Binary combinations of four protein subunits with different catalytic specificities explain the relationship between six basic glutathione S-transferases in rat liver cytosol.

Authors:  B Mannervik; H Jensson
Journal:  J Biol Chem       Date:  1982-09-10       Impact factor: 5.157

7.  The role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents.

Authors:  L F Chasseaud
Journal:  Adv Cancer Res       Date:  1979       Impact factor: 6.242

8.  Glutathione S-transferase isozymes of mouse intestine: differential induction by 2(3)-tert-butyl-4-hydroxyanisole.

Authors:  R E Parchment; A M Benson
Journal:  Biochem Biophys Res Commun       Date:  1984-03-30       Impact factor: 3.575

9.  Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA.

Authors:  W R Pearson; J J Windle; J F Morrow; A M Benson; P Talalay
Journal:  J Biol Chem       Date:  1983-02-10       Impact factor: 5.157

10.  Evidence that the Yb subunits of hepatic glutathione transferases represent two different but related families of polypeptides.

Authors:  D Beale; D J Meyer; J B Taylor; B Ketterer
Journal:  Eur J Biochem       Date:  1983-12-01
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  13 in total

1.  Mu-class glutathione transferase from Xenopus laevis: molecular cloning, expression and site-directed mutagenesis.

Authors:  Antonella De Luca; Bartolo Favaloro; Stefania Angelucci; Paolo Sacchetta; Carmine Di Ilio
Journal:  Biochem J       Date:  2002-08-01       Impact factor: 3.857

2.  Glutathione transferase isoenzymes from Bufo bufo embryos at an early developmental stage.

Authors:  C Di Ilio; A Aceto; T Bucciarelli; B Dragani; S Angelucci; M Miranda; A Poma; F Amicarelli; D Barra; G Federici
Journal:  Biochem J       Date:  1992-04-01       Impact factor: 3.857

3.  Purification and properties of glutathione S-transferase from the pike liver.

Authors:  E V Borvinskaya; N N Nemova; L P Smirnov
Journal:  Dokl Biol Sci       Date:  2013-03-12

4.  Molecular cloning and overexpression of a glutathione transferase gene from Proteus mirabilis.

Authors:  B Perito; N Allocati; E Casalone; M Masulli; B Dragani; M Polsinelli; A Aceto; C Di Ilio
Journal:  Biochem J       Date:  1996-08-15       Impact factor: 3.857

5.  Mouse hepatic glutathione transferase isoenzymes and their differential induction by anticarcinogens. Specificities of butylated hydroxyanisole and bisethylxanthogen as inducers of glutathione transferases in male and female CD-1 mice.

Authors:  A M Benson; M J Hunkeler; J L York
Journal:  Biochem J       Date:  1989-08-01       Impact factor: 3.857

6.  Molecular cloning, expression and site-directed mutagenesis of glutathione S-transferase from Ochrobactrum anthropi.

Authors:  B Favaloro; A Tamburro; S Angelucci; A D Luca; S Melino; C di Ilio; D Rotilio
Journal:  Biochem J       Date:  1998-11-01       Impact factor: 3.857

7.  In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids.

Authors:  Jose L Perez; Guddarangavvanahally K Jayaprakasha; Adriana Cadena; Elvia Martinez; Hassan Ahmad; Bhimanagouda S Patil
Journal:  BMC Complement Altern Med       Date:  2010-09-17       Impact factor: 3.659

8.  Hepatic glutathione S-transferases in mice fed on a diet containing the anticarcinogenic antioxidant butylated hydroxyanisole. Isolation of mouse glutathione S-transferase heterodimers by gradient elution of the glutathione-Sepharose affinity matrix.

Authors:  J D Hayes; L A Kerr; S D Peacock; A D Cronshaw; L I McLellan
Journal:  Biochem J       Date:  1991-07-15       Impact factor: 3.857

9.  Limonin methoxylation influences the induction of glutathione S-transferase and quinone reductase.

Authors:  Jose Luis Perez; G K Jayaprakasha; Violeta Valdivia; Diana Munoz; Deepak V Dandekar; Hassan Ahmad; Bhimanagouda S Patil
Journal:  J Agric Food Chem       Date:  2009-06-24       Impact factor: 5.279

Review 10.  In vitro analysis of metabolic predisposition to drug hypersensitivity reactions.

Authors:  R J Riley; J S Leeder
Journal:  Clin Exp Immunol       Date:  1995-01       Impact factor: 4.330
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