Literature DB >> 31469287

Copper-Catalyzed Regioselective sp3 C-H Azidation of Alkyl Substituents of Indoles and Tetrahydrocarbazoles.

Liwu Huang1, Xudong Xun1, Man Zhao1, Jianzhong Xue1, Guofeng Li1, Liang Hong1.   

Abstract

An efficient regioselective sp3 C-H azidation is developed using CuBr as the catalyst and Zhdankin azidoiodinane as the "N3" source. Under simple and mild reaction conditions, the azido group could be successfully incorporated into the sp3 C-H alkyl substituents of indoles and tetrahydrocarbazoles.

Entities:  

Year:  2019        PMID： 31469287     DOI： 10.1021/acs.joc.9b01742

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Mechanistic Investigation of the Iron-Catalyzed Azidation of Alkyl C(sp3)-H Bonds with Zhdankin's λ3-Azidoiodane.

Authors:  Craig S Day; Alexander Fawcett; Ruchira Chatterjee; John F Hartwig
Journal:  J Am Chem Soc       Date:  2021-09-24       Impact factor: 16.383

2.  Iron-catalyzed tandem reaction of C-Se bond coupling/selenosulfonation of indols with benzeneselenols.

Authors:  Senling Guan; Yue Chen; Hongjie Wu; Runsheng Xu
Journal:  RSC Adv       Date:  2020-07-20       Impact factor: 4.036

Review 3.  Progress and prospects in copper-catalyzed C-H functionalization.

Authors:  Thaipparambil Aneeja; Mohan Neetha; C M A Afsina; Gopinathan Anilkumar
Journal:  RSC Adv       Date:  2020-09-17       Impact factor: 4.036
  3 in total

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