Literature DB >> 31469009

Xyloglucan, hibiscus and propolis to reduce symptoms and antibiotics use in recurrent UTIs: a prospective study.

Tommaso Cai1, Irene Tamanini1, Andrea Cocci2, Fabrizio Di Maida2, Patrizio Caciagli3, Serena Migno4, Liliana Mereu4, Saverio Tateo4, Gianni Malossini1, Alessandro Palmieri5, Paolo Verze5, Vincenzo Mirone5, Truls E Bjerklund Johansen6.   

Abstract

Aim: To evaluate the efficacy of a medical device containing xyloglucan, hibiscus and propolis in the management of recurrent urinary tract infections (rUTIs). Patients & methods: Sixty-one women affected by rUTIs received this medical device, one capsule a day for 15 days (one cycle every month, for 6 months), in an observational, prospective study. Clinical and microbiological evaluations were performed at baseline and 1, 3 and 6 months from enrolment.
Results: At first follow-up, 41 reported a clinical improvement and a return to their clinical status before UTI, while 47 and 51 did so at the second and third follow-up evaluations. A statistically significant clinical improvement was reported at each follow-up visit (quality of life [QoL] 94.2 vs 98.6; QoL 94.1 vs 98.7; QoL 94.2 vs 99.1; p < 0.001). A statistically significant reduction in antibiotic use was reported.
Conclusion: This medical device is able to improve quality of life in women with rUTIs, reduce recurrences and antibiotic use.

Entities:  

Keywords:  antibiotic stewardship; ibiscus; propolis; quality of life; urinary tract infections; xyloglucan

Mesh:

Substances:

Year:  2019        PMID: 31469009     DOI: 10.2217/fmb-2019-0145

Source DB:  PubMed          Journal:  Future Microbiol        ISSN: 1746-0913            Impact factor:   3.165


  2 in total

Review 1.  A non-pharmacological approach to the treatment of urinary tract infections: case reports with Utipro® Plus.

Authors:  Tommaso Cai; Cristian Konstantinidis; Sam Ward
Journal:  Drugs Context       Date:  2021-05-24

Review 2.  Xyloglucan, Hibiscus and Propolis in the Management of Uncomplicated Lower Urinary Tract Infections: A Systematic Review and Meta-Analysis.

Authors:  Tommaso Cai; Umberto Anceschi; Irene Tamanini; Serena Migno; Michele Rizzo; Giovanni Liguori; Alejandro Garcia-Larrosa; Alessandro Palmieri; Paolo Verze; Vincenzo Mirone; Truls E Bjerklund Johansen
Journal:  Antibiotics (Basel)       Date:  2021-12-23
  2 in total

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