Hanson Zhao1, Howard H Kim2. 1. Division of Urology, Department of Surgery, Cedars-Sinai Medical Center, 8635 West 3rd Street, Suite 690W, Los Angeles, CA, 90048, USA. 2. Division of Urology, Department of Surgery, Cedars-Sinai Medical Center, 8635 West 3rd Street, Suite 690W, Los Angeles, CA, 90048, USA. KimHH@csmns.org.
Abstract
PURPOSE OF REVIEW: Lower urinary tract symptoms (LUTS) and sexual health have common links. Medical and surgical treatments for LUTS can significantly affect various domains of sexual health including erectile function, ejaculatory function, and libido. This review summarizes recent findings. RECENT FINDINGS: Current literature demonstrates a strong association between LUTS, sexual health, and metabolic syndrome. The role of miRNA is also being investigated. Combination medical therapy with phosphodiesterase 5 inhibitors (PDE5-I) shows promise but needs further investigation. Newer surgical therapies for benign prostatic hyperplasia (BPH) aim to preserve sexual function without sacrificing efficacy and durability. Although we are beginning to acknowledge the link between LUTS and sexual health, a better understanding of the underlying biochemistry is needed. Only then can more effective therapies be developed. Further prospective studies should focus on the long-term durability and safety of treatments for both conditions.
PURPOSE OF REVIEW: Lower urinary tract symptoms (LUTS) and sexual health have common links. Medical and surgical treatments for LUTS can significantly affect various domains of sexual health including erectile function, ejaculatory function, and libido. This review summarizes recent findings. RECENT FINDINGS: Current literature demonstrates a strong association between LUTS, sexual health, and metabolic syndrome. The role of miRNA is also being investigated. Combination medical therapy with phosphodiesterase 5 inhibitors (PDE5-I) shows promise but needs further investigation. Newer surgical therapies for benign prostatic hyperplasia (BPH) aim to preserve sexual function without sacrificing efficacy and durability. Although we are beginning to acknowledge the link between LUTS and sexual health, a better understanding of the underlying biochemistry is needed. Only then can more effective therapies be developed. Further prospective studies should focus on the long-term durability and safety of treatments for both conditions.
Entities:
Keywords:
Benign prostatic hyperplasia; Erectile dysfunction; Lower urinary tract symptoms; Metabolic syndrome; Sexual health
Authors: João M Pisco; Tiago Bilhim; Luis C Pinheiro; Lucia Fernandes; Jose Pereira; Nuno V Costa; Marisa Duarte; António G Oliveira Journal: J Vasc Interv Radiol Date: 2016-06-16 Impact factor: 3.464
Authors: Claus G Roehrborn; Jack Barkin; Steven N Gange; Neal D Shore; Jonathan L Giddens; Damien M Bolton; Barrett E Cowan; Anthony L Cantwell; Kevin T McVary; Alexis E Te; Shahram S Gholami; William G Moseley; Peter T Chin; William T Dowling; Sheldon J Freedman; Peter F Incze; K Scott Coffield; Sean Herron; Prem Rashid; Daniel B Rukstalis Journal: Can J Urol Date: 2017-06 Impact factor: 1.344
Authors: Adolfo Casabé; Claus G Roehrborn; Luigi F Da Pozzo; Sebastian Zepeda; R Jonathan Henderson; Sebastian Sorsaburu; Carsten Henneges; David G Wong; Lars Viktrup Journal: J Urol Date: 2013-10-02 Impact factor: 7.450