Literature DB >> 31467795

In vivo terahertz imaging to evaluate scar treatment strategies: silicone gel sheeting.

Jiarui Wang1, Qiushuo Sun1, Rayko I Stantchev1, Tor-Wo Chiu2, Anil T Ahuja3, Emma Pickwell-MacPherson1,4.   

Abstract

Silicone gel sheeting (SGS) is widely used for scar treatment; however, studies showing its interaction with skin and efficacy of scar treatment are still lacking. THz light is non-ionizing and highly sensitive to changes in water content and thus skin hydration. In this work, we use in-vivo THz imaging to monitor how SGS affects the THz response of human skin during occlusion, and the associated THz reflectivity and refractive index changes are presented. We find that SGS effectively hydrates the skin beneath it, with minimal lateral effects beyond the sheeting. Our work demonstrates that THz imaging is able to detect the subtle hydration changes on the surface of human skin caused by SGS, and it has the potential to be used to evaluate different scar treatment strategies.

Entities:  

Year:  2019        PMID: 31467795      PMCID: PMC6706020          DOI: 10.1364/BOE.10.003584

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  3 in total

1.  Co-registered combined OCT and THz imaging to extract depth and refractive index of a tissue-equivalent test object.

Authors:  A J Fitzgerald; X Tie; M J Hackmann; B Cense; A P Gibson; V P Wallace
Journal:  Biomed Opt Express       Date:  2020-02-19       Impact factor: 3.732

Review 2.  Evidence-based therapy in hypertrophic scars: An update of a systematic review.

Authors:  Sebastian P Nischwitz; Katharina Rauch; Hanna Luze; Elisabeth Hofmann; Alexander Draschl; Petra Kotzbeck; Lars-Peter Kamolz
Journal:  Wound Repair Regen       Date:  2020-06-15       Impact factor: 3.617

3.  Monitoring the Effect of Transdermal Drug Delivery Patches on the Skin Using Terahertz Sensing.

Authors:  Hannah Lindley-Hatcher; Jiarui Wang; Arturo I Hernandez-Serrano; Joseph Hardwicke; Gabit Nurumbetov; David M Haddleton; Emma Pickwell-MacPherson
Journal:  Pharmaceutics       Date:  2021-12-01       Impact factor: 6.321

  3 in total

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