| Literature DB >> 31466590 |
Shervin A Etemad1, Anna K Dewan2.
Abstract
Kaposi sarcoma (KS) is an angioproliferative mesenchymal neoplasm caused by Kaposi sarcoma-related herpesvirus. This review outlines our current understanding of the epidemiology, pathogenesis, clinical presentation, and staging for this disease. Recent research has informed a more comprehensive understanding of the epidemiology of KS in the post-antiretroviral therapy era, and highlights the continued need to better characterize the African endemic subtype. Advances in clinical oncology, including checkpoint inhibitors and new skin-directed therapies, have translated into exciting new developments for the future of KS treatment options.Entities:
Keywords: AIDS; HHV8; HIV; Immunosuppression; Kaposi sarcoma; Sarcoma
Mesh:
Substances:
Year: 2019 PMID: 31466590 DOI: 10.1016/j.det.2019.05.008
Source DB: PubMed Journal: Dermatol Clin ISSN: 0733-8635 Impact factor: 3.478