Literature DB >> 31464012

Visible-Light-Promoted Cascade Radical Cyclization: Synthesis of 1,4-Diketones Containing Chroman-4-One Skeletons.

Xiang-Kui He1, Bao-Gui Cai1, Qing-Qing Yang2, Long Wang2, Jun Xuan1,3.   

Abstract

A visible-light-induced cascade radical cyclization of aroyl chlorides with 2-(allyloxy)-benzaldehyde derivatives has been developed. The method takes advantages of unactivated C=C bonds as the acyl radical acceptors and offers a mild and green approach for the synthesis of 1,4-diketones bearing biologically important chroman-4-one skeletons with moderate to good yields.
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  1,4-Diketones; Acyl radical; Photoredox catalysis; Radical cyclization; Visible light

Year:  2019        PMID： 31464012     DOI： 10.1002/asia.201901078

Source DB:  PubMed          Journal:  Chem Asian J        ISSN： 1861-471X


  2 in total

1.  Mild synthesis of isoxazoline derivatives via an efficient [4 + 1] annulation reaction of transient nitrosoalkenes and sulfur ylides.

Authors:  Ting-Bi Hua; Cheng-Xiong Liu; Wei-Min Hu; Long Wang; Qing-Qing Yang
Journal:  Sci Rep       Date:  2021-01-22       Impact factor: 4.379

2.  Metal-free synthesis of phosphinoylchroman-4-ones via a radical phosphinoylation-cyclization cascade mediated by K2S2O8.

Authors:  Qiang Liu; Weibang Lu; Guanqun Xie; Xiaoxia Wang
Journal:  Beilstein J Org Chem       Date:  2020-08-12       Impact factor: 2.883
  2 in total

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