Literature DB >> 31462514

A wolf in sheep's clothing: unmasking the lanosterol-induced degradation of HMG-CoA reductase.

Hudson W Coates1, Andrew J Brown2.   

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Year:  2019        PMID: 31462514      PMCID: PMC6795080          DOI: 10.1194/jlr.C119000358

Source DB:  PubMed          Journal:  J Lipid Res        ISSN: 0022-2275            Impact factor:   5.922


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  17 in total

Review 1.  Retrospective on Cholesterol Homeostasis: The Central Role of Scap.

Authors:  Michael S Brown; Arun Radhakrishnan; Joseph L Goldstein
Journal:  Annu Rev Biochem       Date:  2017-08-25       Impact factor: 23.643

2.  Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing.

Authors:  Liang Chen; Mei-Yan Ma; Ming Sun; Lu-Yi Jiang; Xue-Tong Zhao; Xian-Xiu Fang; Sin Man Lam; Guang-Hou Shui; Jie Luo; Xiong-Jie Shi; Bao-Liang Song
Journal:  J Lipid Res       Date:  2019-08-27       Impact factor: 5.922

3.  Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol.

Authors:  Bao-Liang Song; Norman B Javitt; Russell A DeBose-Boyd
Journal:  Cell Metab       Date:  2005-03       Impact factor: 27.287

4.  Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis.

Authors:  Jenny Wong; Carmel M Quinn; Ingrid C Gelissen; Andrew J Brown
Journal:  J Biol Chem       Date:  2007-11-02       Impact factor: 5.157

5.  Chemical structure of sterols that activate oocyte meiosis.

Authors:  A G Byskov; C Y Andersen; L Nordholm; H Thøgersen; G Xia; O Wassmann; J V Andersen; E Guddal; T Roed
Journal:  Nature       Date:  1995-04-06       Impact factor: 49.962

6.  Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.

Authors:  Yvonne Lange; Daniel S Ory; Jin Ye; Michael H Lanier; Fong-Fu Hsu; Theodore L Steck
Journal:  J Biol Chem       Date:  2007-11-16       Impact factor: 5.157

7.  Biological activity of some oxygenated sterols.

Authors:  A A Kandutsch; H W Chen; H J Heiniger
Journal:  Science       Date:  1978-08-11       Impact factor: 47.728

8.  Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs.

Authors:  Andrew D Nguyen; Jeffrey G McDonald; Richard K Bruick; Russell A DeBose-Boyd
Journal:  J Biol Chem       Date:  2007-07-16       Impact factor: 5.157

9.  Identification of natural RORγ ligands that regulate the development of lymphoid cells.

Authors:  Fabio R Santori; Pengxiang Huang; Serge A van de Pavert; Eugene F Douglass; David J Leaver; Brad A Haubrich; Rok Keber; Gregor Lorbek; Tanja Konijn; Brittany N Rosales; Damjana Rozman; Simon Horvat; Alain Rahier; Reina E Mebius; Fraydoon Rastinejad; W David Nes; Dan R Littman
Journal:  Cell Metab       Date:  2015-02-03       Impact factor: 27.287

10.  Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways.

Authors:  Matthew A Mitsche; Jeffrey G McDonald; Helen H Hobbs; Jonathan C Cohen
Journal:  Elife       Date:  2015-06-26       Impact factor: 8.140

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  4 in total

Review 1.  Post-translational control of the long and winding road to cholesterol.

Authors:  Laura J Sharpe; Hudson W Coates; Andrew J Brown
Journal:  J Biol Chem       Date:  2020-12-18       Impact factor: 5.157

Review 2.  Post-translational control of the long and winding road to cholesterol.

Authors:  Laura J Sharpe; Hudson W Coates; Andrew J Brown
Journal:  J Biol Chem       Date:  2020-10-13       Impact factor: 5.157

3.  SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.

Authors:  Tobiloba E Oni; Giulia Biffi; Lindsey A Baker; Yuan Hao; Claudia Tonelli; Tim D D Somerville; Astrid Deschênes; Pascal Belleau; Chang-Il Hwang; Francisco J Sánchez-Rivera; Hilary Cox; Erin Brosnan; Abhishek Doshi; Rebecca P Lumia; Kimia Khaledi; Youngkyu Park; Lloyd C Trotman; Scott W Lowe; Alexander Krasnitz; Christopher R Vakoc; David A Tuveson
Journal:  J Exp Med       Date:  2020-09-07       Impact factor: 14.307

4.  Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.

Authors:  Ryan G Snodgrass; Yvonne Benatzy; Tobias Schmid; Dmitry Namgaladze; Malwina Mainka; Nils Helge Schebb; Dieter Lütjohann; Bernhard Brüne
Journal:  Cell Death Differ       Date:  2020-11-11       Impact factor: 15.828

  4 in total

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