Literature DB >> 31461100

Cuprous binding promotes interaction of copper transport protein hCTR1 with cell membranes.

Yang Yang1, Yang Zhu1, Hongze Hu1, Lanjun Cheng1, Manman Liu1, Guolin Ma2, Siming Yuan1, Peixin Cui3, Yangzhong Liu1.   

Abstract

Cu(i) binds to the N-terminal metal binding domain (MBD) of hCTR1 and induces its conformational change, which promotes the interaction of the MBD with cell membranes. The membrane interaction was confirmed in living cells. This process could be the first step to initiate the cellular uptake of copper ions by hCTR1.

Entities:  

Year:  2019        PMID： 31461100     DOI： 10.1039/c9cc04859f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Interactions between mitochondria-damaging platinum(IV) prodrugs and cytochrome c.

Authors:  Amarasooriya M D S Jayawardhana; Yao-Rong Zheng
Journal:  Dalton Trans       Date:  2022-02-01       Impact factor: 4.390

2.  Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion.

Authors:  Gulshan Walke; Jana Aupič; Hadeel Kashoua; Pavel Janoš; Shelly Meron; Yulia Shenberger; Zena Qasem; Lada Gevorkyan-Airapetov; Alessandra Magistrato; Sharon Ruthstein
Journal:  Biophys J       Date:  2022-02-22       Impact factor: 3.699

Review 3.  Quantitative Analysis of the Interactions of Metal Complexes and Amphiphilic Systems: Calorimetric, Spectroscopic and Theoretical Aspects.

Authors:  Rossella Migliore; Tarita Biver; Giampaolo Barone; Carmelo Sgarlata
Journal:  Biomolecules       Date:  2022-03-07

4.  A Deeper Insight in Metal Binding to the hCtr1 N-terminus Fragment: Affinity, Speciation and Binding Mode of Binuclear Cu2+ and Mononuclear Ag+ Complex Species.

Authors:  Antonio Magrì; Giovanni Tabbì; Irina Naletova; Francesco Attanasio; Giuseppe Arena; Enrico Rizzarelli
Journal:  Int J Mol Sci       Date:  2022-03-08       Impact factor: 5.923
  4 in total

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