Literature DB >> 31455961

Determination of nucleobase-pairing free energies from rotamer equilibria of 2-(methylamino)pyrimidines.

Jakub Radek Štoček1, Kateřina Bártová1, Lucie Čechová1, Michal Šála1, Ondřej Socha1, Zlatko Janeba1, Martin Dračínský1.   

Abstract

A fast straightforward method for the determination of free energies of modified nucleobase pairing is proposed. The method is based on the nuclear magnetic resonance (NMR) spectroscopy monitoring of conformational changes of 2-(methylamino)-pyrimidines upon intermolecular binding.

Entities:  

Year:  2019        PMID: 31455961     DOI: 10.1039/c9cc05513d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Tautomerism of Guanine Analogues.

Authors:  Jakub Radek Štoček; Martin Dračínský
Journal:  Biomolecules       Date:  2020-01-22
  1 in total

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