Literature DB >> 31455591

[Place of radiotherapy and surgery in the treatment of cervical cancer patients].

P Annede1, S Gouy2, C Haie-Meder3, P Morice4, C Chargari5.   

Abstract

The treatment of cervical cancer patients relies on surgery and radiotherapy (according to the stage) and requires a multimodal discussion before any treatment to avoid adding the morbidities of each individual intervention and to optimize functional and oncological outcomes. The places of surgery and radiotherapy have been highlighted in recent international guidelines. For early stage tumors, an exclusive surgery with or without fertility sparing (according to well defined criteria) is the therapeutic standard. For tumors with risk factors (measuring more than 2cm in size and/or presence of lymphovascular invasion) a preoperative brachytherapy can be proposed to minimize the need for postoperative external beam radiotherapy and optimize local control. For locally advanced disease, the standard treatment relies on chemoradiation followed by a brachytherapy boost. A primary paraaortic lymph node dissection may guide radiotherapy volumes and is useful to identify patients requiring a para-aortic radiotherapy. The technical evolutions of surgical approaches and technological improvement of radiotherapy and brachytherapy should be analyzed in the context of prospective studies. We review the literature on the respective places of radiotherapy and surgery for the treatment of cervical cancer.
Copyright © 2019 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Brachytherapy; Cancer du col utérin; Cervical cancer; Chirurgie; Curiethérapie; Radiotherapy; Radiothérapie; Surgery

Mesh:

Year:  2019        PMID: 31455591     DOI: 10.1016/j.canrad.2019.07.151

Source DB:  PubMed          Journal:  Cancer Radiother        ISSN: 1278-3218            Impact factor:   1.018


  3 in total

1.  Use of Baseline 18 F-FDG PET/CT to Identify Initial Sub-Volumes Associated With Local Failure After Concomitant Chemoradiotherapy in Locally Advanced Cervical Cancer.

Authors:  François Lucia; Omar Miranda; Ronan Abgral; Vincent Bourbonne; Gurvan Dissaux; Olivier Pradier; Mathieu Hatt; Ulrike Schick
Journal:  Front Oncol       Date:  2020-05-07       Impact factor: 6.244

2.  Providing Patients with Locally Advanced Cervical Cancer Access to Brachytherapy: Experience from a Referral Network for Women Treated in Overseas France.

Authors:  Rita Bentahila; Elie Rassy; Samir Achkar; Florence Sacino; Stefanos Bougas; Alexis Vallard; Vincent Vinh-Hung; Johan Encaoua; Pierre Gustin; Sylvie Mengue; Patricia Pautier; Philippe Morice; Sébastien Gouy; Sophie Espenel; Eric Deutsch; Cyrus Chargari
Journal:  Cancers (Basel)       Date:  2022-06-14       Impact factor: 6.575

3.  LncRNA HOXA-AS2 Activates the Notch Pathway to Promote Cervical Cancer Cell Proliferation and Migration.

Authors:  Qunxiong Wu; Shentao Lu; Li Zhang; Lingjun Zhao
Journal:  Reprod Sci       Date:  2021-06-02       Impact factor: 3.060

  3 in total

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