Literature DB >> 31453540

Effectiveness of electrical stimulation after administration of botulinum toxin in children with spastic diplegic cerebral palsy: A prospective, randomized clinical study.

Pembe Yiğitoğlu1, Erkan Kozanoğlu2.   

Abstract

OBJECTIVES: The aim of the study was to investigate the effectiveness of electrical stimulation to agonist muscles after injection of Botulinum toxin A (BTX-A) in children with spastic diplegic cerebral palsy (SDCP). PATIENTS AND METHODS: Between October 2009 and October 2010, 38 patients with SDCP (19 males, 19 females; mean age 6.3 years; range, 4 to 10 years) were included. The patients were able to walk independently or with minimal assistance by foot equine and had spasticity in the calf muscles between Grades 1+ and 3 according to the Modified Ashworth Scale (MAS). The patients received either BTX-A injection + electrical stimulation (Group 1, n=19) or BTX-A injection alone (Group 2, n=19). All patients were evaluated using the MAS, Penn Spasm Frequency Scale (PSFS), Gross Motor Function Measure-88 (GMFM-88) (Dimensions D and E), and walking velocity.
RESULTS: A decrease in spasticity was evident for the right, left, and bilateral lower extremities for both groups (p<0.05). There were no statistically significant differences in the MAS, PSFS, GMFM-88 (Dimensions D and E), and walking velocity between the groups.
CONCLUSION: Our study results showed that both patient groups benefited from the treatment and the administration of electrical stimulation to the gastrocnemius motor points produced no additional benefit for patients with SDCP.

Entities:  

Keywords:  Botulinum toxin; cerebral palsy; electrical stimulation; spasticity

Year:  2019        PMID: 31453540      PMCID: PMC6648179          DOI: 10.5606/tftrd.2019.2236

Source DB:  PubMed          Journal:  Turk J Phys Med Rehabil        ISSN: 2587-1250


  25 in total

1.  Validation of a model of gross motor function for children with cerebral palsy.

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2.  Influence of nerve-ending activity and of drugs on the rate of paralysis of rat diaphragm preparations by Cl. botulinum type A toxin.

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3.  Clinical management of spasticity.

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4.  Nerve stimulation boosts botulinum toxin action in spasticity.

Authors:  Emma Frasson; Alberto Priori; Barbara Ruzzante; Giuseppe Didonè; Laura Bertolasi
Journal:  Mov Disord       Date:  2005-05       Impact factor: 10.338

Review 5.  Cerebral palsy-definition, classification, etiology and early diagnosis.

Authors:  Chitra Sankar; Nandini Mundkur
Journal:  Indian J Pediatr       Date:  2005-10       Impact factor: 1.967

6.  Low-dose botulinum toxin with short-term electrical stimulation in poststroke spastic drop foot: a preliminary study.

Authors:  Suheda Bayram; Koncuy Sivrioglu; Necdet Karli; Orhan Ozcan
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Review 7.  Botulinum toxin A treatment of adult upper and lower limb spasticity.

Authors:  S Hesse; B Brandi-Hesse; A Bardeleben; C Werner; M Funk
Journal:  Drugs Aging       Date:  2001       Impact factor: 3.923

8.  Validity of a 1 minute walk test for children with cerebral palsy.

Authors:  Brona C McDowell; Claire Kerr; Jackie Parkes; Aidan Cosgrove
Journal:  Dev Med Child Neurol       Date:  2005-11       Impact factor: 5.449

9.  Botulinum toxin and short-term electrical stimulation in the treatment of equinus in cerebral palsy.

Authors:  C Detrembleur; T M Lejeune; A Renders; P Y K Van Den Bergh
Journal:  Mov Disord       Date:  2002-01       Impact factor: 10.338

Review 10.  Proposed definition and classification of cerebral palsy, April 2005.

Authors:  Martin Bax; Murray Goldstein; Peter Rosenbaum; Alan Leviton; Nigel Paneth; Bernard Dan; Bo Jacobsson; Diane Damiano
Journal:  Dev Med Child Neurol       Date:  2005-08       Impact factor: 5.449

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  3 in total

Review 1.  Relationship between ankle function and walking ability for children and young adults with cerebral palsy: A systematic review of deficits and targeted interventions.

Authors:  Benjamin C Conner; Nushka M Remec; Cassidy M Michaels; Chase W Wallace; Emily Andrisevic; Zachary F Lerner
Journal:  Gait Posture       Date:  2021-10-25       Impact factor: 2.840

Review 2.  Electrical Stimulation of Injected Muscles to Boost Botulinum Toxin Effect on Spasticity: Rationale, Systematic Review and State of the Art.

Authors:  Alessandro Picelli; Mirko Filippetti; Giorgio Sandrini; Cristina Tassorelli; Roberto De Icco; Nicola Smania; Stefano Tamburin
Journal:  Toxins (Basel)       Date:  2021-04-23       Impact factor: 4.546

3.  Efficacy of conservative treatment for spastic cerebral palsy children with equinus gait: a systematic review and meta-analysis.

Authors:  Krongkaew Klaewkasikum; Tanyaporn Patathong; Patarawan Woratanarat; Thira Woratanarat; Kunlawat Thadanipon; Sasivimol Rattanasiri; Ammarin Thakkinstian
Journal:  J Orthop Surg Res       Date:  2022-09-08       Impact factor: 2.677

  3 in total

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