| Literature DB >> 3145120 |
C de la Piedra1, J Larrañaga, N Castro, C Horcajada, A Rapado, J L Herrera Pombo, E Carbó.
Abstract
Plasma osteocalcin (BGP), growth hormone (GH), and somatomedin C(SmC) were measured in 12 patients with acromegaly [7 clinically active (aA), 5 cured (cA)] and 9 control subjects (C). Basal plasma values for the three parameters were higher in aA than in C and in cA. No significant difference was found between cA and C. A significant linear correlation between BGP and GH and between BGP and SmC was obtained. These results suggest an effect of GH on BGP synthesis, possibly mediated by SmC, although a direct effect of GH on bone cannot be excluded.Entities:
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Year: 1988 PMID: 3145120 DOI: 10.1007/bf02555167
Source DB: PubMed Journal: Calcif Tissue Int ISSN: 0171-967X Impact factor: 4.333