Literature DB >> 31448187

Providers' Perspectives on Adherence to Hormonal Therapy in Breast Cancer Survivors. Is there a Role for the Digital Health Feedback System?

Alejandra Hurtado de Mendoza1, Mark Cabling2, Asma Dilawari3, Jeanine W Turner4, Nicole Fernández4, Alesha Henderson5, Qi Zhu1, Sara Gómez1, Vanessa B Sheppard5.   

Abstract

OBJECTIVE: Despite the benefits of hormonal therapy (HT) adherence remains suboptimal in ER positive breast cancer patients. Medication adherence is challenging to assess and tends to be overestimated. The Digital Health Feedback System (DHFS) consists of an ingestible sensor attached to a pill that sends intake date and time to a smart phone or computer. Patients can share this information with health care providers and other persons. The DHFS can also send reminders. This mixed methods study examined providers' perceptions of HT medication adherence. The potential role of the DHFS in enhancing medication tracking and adherence was also explored.
METHODS: We conducted semi-structured interviews with key informants (N=10). Questions examined perceptions about adherence barriers and facilitators, challenges tracking adherence, and views on the DHFS. Findings informed the development of a survey that was administered online (N=19).
RESULTS: Providers emphasized the importance of fostering open and trustful communication around adherence. The most mentioned challenges to assessing adherence were the patient not disclosing discontinuation immediately (78.9%) and over-reporting adherence (57.9%). The perceived potential benefits of DHFS were the ability to track adherence better (94.7%) and reminders to take the medication (68.4%). Safety to ingest a sensor was as a major perceived barrier (8 4.2%).
CONCLUSION: Interventions that target providers and doctor-patient communication are warranted to enhance adherence and reduce communication delays around HT discontinuation. PRACTICE IMPLICATIONS: DHFS has the potential to enhance HT adherence by directly targeting barriers. Future studies should also examine the feasibility of adopting the DHFS with cancer patients.

Entities:  

Keywords:  Digital Health Feedback System; Patient-doctor communication; hormonal therapy adherence

Year:  2018        PMID: 31448187      PMCID: PMC6707743          DOI: 10.1007/s12553-018-0267-x

Source DB:  PubMed          Journal:  Health Technol (Berl)        ISSN: 2190-7196


  38 in total

1.  Intentional and non-intentional non-adherence to medication amongst breast cancer patients.

Authors:  Louise Atkins; Lesley Fallowfield
Journal:  Eur J Cancer       Date:  2006-04-27       Impact factor: 9.162

Review 2.  Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice.

Authors:  K C Farmer
Journal:  Clin Ther       Date:  1999-06       Impact factor: 3.393

3.  Discussing adjuvant cancer therapy.

Authors:  N Leighl; M Gattellari; P Butow; R Brown; M H Tattersall
Journal:  J Clin Oncol       Date:  2001-03-15       Impact factor: 44.544

4.  Adherence beliefs among breast cancer patients taking tamoxifen.

Authors:  Elizabeth A Grunfeld; Myra S Hunter; Pooja Sikka; Sangeeta Mittal
Journal:  Patient Educ Couns       Date:  2005-10

5.  Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials.

Authors: 
Journal:  Lancet       Date:  2005 May 14-20       Impact factor: 79.321

Review 6.  Recognition and management of treatment-related side effects for breast cancer patients receiving adjuvant endocrine therapy.

Authors:  David Cella; Lesley J Fallowfield
Journal:  Breast Cancer Res Treat       Date:  2007-09-18       Impact factor: 4.872

7.  Insight into barriers against optimal adherence to oral hormonal therapy in women with breast cancer.

Authors:  Margaret C Kirk; Clifford A Hudis
Journal:  Clin Breast Cancer       Date:  2008-04       Impact factor: 3.225

8.  Adherence to tamoxifen over the five-year course.

Authors:  Timothy L Lash; Matthew P Fox; Jennifer L Westrup; Aliza K Fink; Rebecca A Silliman
Journal:  Breast Cancer Res Treat       Date:  2006-03-16       Impact factor: 4.872

9.  Patient centered experiences in breast cancer: predicting long-term adherence to tamoxifen use.

Authors:  Katherine L Kahn; Eric C Schneider; Jennifer L Malin; John L Adams; Arnold M Epstein
Journal:  Med Care       Date:  2007-05       Impact factor: 2.983

10.  Oncologist-patient discussion of adjuvant hormonal therapy in breast cancer: results of a linguistic study focusing on adherence and persistence to therapy.

Authors:  Brad Davidson; Victor Vogel; Lawrence Wickerham
Journal:  J Support Oncol       Date:  2007-03
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  3 in total

1.  A Novel Digital Pill System for Medication Adherence Measurement and Reporting: Usability Validation Study.

Authors:  Susan L Baumgartner; D Eric Buffkin; Elise Rukavina; Jason Jones; Elizabeth Weiler; Tony C Carnes
Journal:  JMIR Hum Factors       Date:  2021-11-08

Review 2.  Ingestible electronic sensors to measure instantaneous medication adherence: A narrative review.

Authors:  Peter R Chai; Clint Vaz; Georgia R Goodman; Hannah Albrechta; Henwei Huang; Rochelle K Rosen; Edward W Boyer; Kenneth H Mayer; Conall O'Cleirigh
Journal:  Digit Health       Date:  2022-02-28

3.  Acceptability of and Willingness to Take Digital Pills by Patients, the Public, and Health Care Professionals: Qualitative Content Analysis of a Large Online Survey.

Authors:  Astrid Chevance; Axel Fortel; Adeline Jouannin; Faustine Denis; Marie-France Mamzer; Philippe Ravaud; Stephanie Sidorkiewicz
Journal:  J Med Internet Res       Date:  2022-02-18       Impact factor: 7.076

  3 in total

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