Literature DB >> 31447917

Non-directed bronchial lavage is a safe method for sampling the respiratory tract in critically ill patient.

B V Bonvento1, J A Rooney2, M O Columb1, B A McGrath1,3, A M Bentley1,3, T W Felton1,3.   

Abstract

Ventilated patients are at risk of acquiring ventilator-associated pneumonia. Various techniques are available for diagnosing ventilator-associated pneumonia including bronchoalveolar lavage, protected specimen brush and non-directed bronchoalveolar lavage. There is a paucity of evidence regarding the safety profile of these techniques, particularly non-directed bronchoalveolar lavage. This service evaluation aimed to establish whether non-directed bronchoalveolar lavage is a safe procedure. A prospective service evaluation of non-directed bronchoalveolar lavage on our adult intensive care unit was undertaken by a senior physiotherapist trained into carrying out the procedure, measuring pre- and post-procedure vital signs including heart rate (HR), tidal volume (VT), systolic blood pressure (SBP) and pulse oximetry (SpO2). Eighty-five episodes in 41 patients were included in the evaluation. There was a statistically significant difference between pre- and immediately post-procedure recordings for all vital signs measure. HR (min-1), means (SD) 87.1 (16.4), 91.5 (16.5), 87.5 (15.9), 87.7 (15.7) respectively pre, immediately, 5 min after and 30 min after procedure (P < 0.01). SBP mmHg, means (SD) 133.9 (26.1), 142.1 (25.6), 136.9 (25.3), 134.8 (23.4) pre, immediately, 5 min and 30 min after procedure (P < 0.01). VT mL, median (range) 0.523 (0.118-1.180), 0.512 (0.131-1.05), 0.519 (0.104-0.95), 0.534 (0.110-1.080) each pre, immediately, 5 min and 30 min post procedure (P < 0.05). SpO2 %, median (range) 98 (89-100), 100 (96-100), 98 (92-100), 97 (90-100) again each pre-, immediately post, 5 and 30 min post-procedure time-points (P < 0.0001). The statistically significant difference was not detected between pre-, 5 or 30 min post-procedure time-points. None of the changes observed were clinically significant and no untoward events happened to any of the subjects included. Non-directed bronchoalveolar lavage is a safe and inexpensive procedure that can be carried out easily in an intensive care setting by a trained physiotherapist, avoiding the need for invasive bronchoscopy.

Entities:  

Keywords:  Non-directed bronchial lavage; mini-lavage; ventilator-associated pneumonia

Year:  2018        PMID: 31447917      PMCID: PMC6693118          DOI: 10.1177/1751143718811113

Source DB:  PubMed          Journal:  J Intensive Care Soc        ISSN: 1751-1437


  19 in total

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Authors:  Tim Felton; Thomas Mount; Paul Chadwick; Murad Ghrew; Paul Dark
Journal:  J Infect       Date:  2010-03-09       Impact factor: 6.072

2.  Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study.

Authors:  Marie-Laurence Lambert; Carl Suetens; Anne Savey; Mercedes Palomar; Michael Hiesmayr; Ingrid Morales; Antonella Agodi; Uwe Frank; Karl Mertens; Martin Schumacher; Martin Wolkewitz
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Review 3.  Clinical and economic consequences of ventilator-associated pneumonia: a systematic review.

Authors:  Nasia Safdar; Cameron Dezfulian; Harold R Collard; Sanjay Saint
Journal:  Crit Care Med       Date:  2005-10       Impact factor: 7.598

4.  Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies.

Authors:  Wilhelmina G Melsen; Maroeska M Rovers; Rolf H H Groenwold; Dennis C J J Bergmans; Christophe Camus; Torsten T Bauer; Ernst W Hanisch; Bengt Klarin; Mirelle Koeman; Wolfgang A Krueger; Jean-Claude Lacherade; Leonardo Lorente; Ziad A Memish; Lee E Morrow; Giuseppe Nardi; Christianne A van Nieuwenhoven; Grant E O'Keefe; George Nakos; Frank A Scannapieco; Philippe Seguin; Thomas Staudinger; Arzu Topeli; Miquel Ferrer; Marc J M Bonten
Journal:  Lancet Infect Dis       Date:  2013-04-25       Impact factor: 25.071

5.  The diagnosis of ventilator-associated pneumonia using non-bronchoscopic, non-directed lung lavages.

Authors:  P G Flanagan; G P Findlay; J T Magee; A Ionescu; R A Barnes; M Smithies
Journal:  Intensive Care Med       Date:  2000-01       Impact factor: 17.440

6.  Implementation of guidelines for management of possible multidrug-resistant pneumonia in intensive care: an observational, multicentre cohort study.

Authors:  Daniel H Kett; Ennie Cano; Andrew A Quartin; Julie E Mangino; Marcus J Zervos; Paula Peyrani; Cynthia M Cely; Kimbal D Ford; Ernesto G Scerpella; Julio A Ramirez
Journal:  Lancet Infect Dis       Date:  2011-01-20       Impact factor: 25.071

7.  Safety and tolerability of nonbronchoscopic lavage in ARDS.

Authors:  Gavin D Perkins; Somnath Chatterjee; Simon Giles; Danny F McAuley; Sarah Quinton; David R Thickett; Fang Gao
Journal:  Chest       Date:  2005-04       Impact factor: 9.410

8.  Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia.

Authors:  Marin H Kollef; Andrew Shorr; Ying P Tabak; Vikas Gupta; Larry Z Liu; R S Johannes
Journal:  Chest       Date:  2005-12       Impact factor: 9.410

9.  International study of the prevalence and outcomes of infection in intensive care units.

Authors:  Jean-Louis Vincent; Jordi Rello; John Marshall; Eliezer Silva; Antonio Anzueto; Claude D Martin; Rui Moreno; Jeffrey Lipman; Charles Gomersall; Yasser Sakr; Konrad Reinhart
Journal:  JAMA       Date:  2009-12-02       Impact factor: 56.272

10.  Surveillance culture utility and safety using low-volume blind bronchoalveolar lavage in the diagnosis of ventilator-associated pneumonia.

Authors:  Robert J Boots; Gael E Phillips; Narelle George; Joan L Faoagali
Journal:  Respirology       Date:  2008-01       Impact factor: 6.424

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Authors:  Lincoln S Smith; Anoopindar Bhalla; Nadir Yehya
Journal:  Pediatr Crit Care Med       Date:  2020-12       Impact factor: 3.971

Review 2.  Practice Guidelines for the Diagnosis of COVID-19-Associated Pulmonary Aspergillosis in an Intensive Care Setting.

Authors:  Zia Hashim; Zafar Neyaz; Rungmei S K Marak; Alok Nath; Soniya Nityanand; Naresh K Tripathy
Journal:  J Intensive Care Med       Date:  2021-10-22       Impact factor: 2.889

  2 in total

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