Literature DB >> 31447530

Chloral Hydrate: Is It Still Being Used? Are There Safer Alternatives?

Matthew Grissinger.   

Abstract

Using chloral hydrate carries a risk of adverse events and compounding errors, and much of the available literature recommends using alternative sedatives for pediatric patients. But evidence regarding the efficacy of chloral hydrate and of alternative agents is conflicting.

Entities:  

Year:  2019        PMID： 31447530      PMCID： PMC6679948     

Source DB:  PubMed          Journal:  P T        ISSN： 1052-1372


  17 in total

1.  A randomized, blinded comparison of chloral hydrate and midazolam sedation in children undergoing echocardiography.

Authors:  D S Wheeler; R A Jensen; W B Poss
Journal:  Clin Pediatr (Phila)       Date:  2001-07       Impact factor: 1.168

2.  Comparing the safety, efficacy and recovery of intranasal midazolam vs. oral chloral hydrate and promethazine.

Authors:  J A Dallman; M A Ignelzi; D M Briskie
Journal:  Pediatr Dent       Date:  2001 Sep-Oct       Impact factor: 1.874

3.  Post-discharge adverse events following pediatric sedation with high doses of oral medication.

Authors:  Luciane Rezende Costa; Paulo Sucasas Costa; Sarah Vieira Brasileiro; Cristiane Baccin Bendo; Cláudia Marina Viegas; Saul Martins Paiva
Journal:  J Pediatr       Date:  2011-12-01       Impact factor: 4.406

4.  Use of chloral hydrate as a sedative for auditory brainstem response testing in a pediatric population.

Authors:  Eirini Avlonitou; Dimitrios G Balatsouras; Eleftherios Margaritis; Polyvios Giannakopoulos; Dimitrios Douniadakis; Michael Tsakanikos
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2011-04-29       Impact factor: 1.675

Review 5.  Procedural sedation and analgesia in the emergency department: what are the risks?

Authors:  Michael A Miller; Phillip Levy; Manish M Patel
Journal:  Emerg Med Clin North Am       Date:  2005-05       Impact factor: 2.264

6.  Adverse sedation events in pediatrics: analysis of medications used for sedation.

Authors:  C J Coté; H W Karl; D A Notterman; J A Weinberg; C McCloskey
Journal:  Pediatrics       Date:  2000-10       Impact factor: 7.124

7.  Chloral hydrate versus midazolam for sedation of children for neuroimaging: a randomized clinical trial.

Authors:  J D'Agostino; T E Terndrup
Journal:  Pediatr Emerg Care       Date:  2000-02       Impact factor: 1.454

8.  A comparison of the efficacy and safety of chloral hydrate versus inhaled anesthesia for sedating infants and toddlers for transthoracic echocardiograms.

Authors:  Susan C Nicolson; Lisa M Montenegro; Meryl S Cohen; Daniel O'Neill; Donna Calfin; Lisa A Jones; David R Jobes
Journal:  J Am Soc Echocardiogr       Date:  2010-01       Impact factor: 5.251

9.  Moderate sedation for echocardiography of preschoolers.

Authors:  Carol Lafayette Roach; Nazia Husain; Jennifer Zabinsky; Elizabeth Welch; Ruchira Garg
Journal:  Pediatr Cardiol       Date:  2010-01-03       Impact factor: 1.655

10.  A comparison of oral chloral hydrate and sublingual midazolam sedation for echocardiogram in children.

Authors:  Thanarat Layangool; Chaisit Sangtawesin; Thawatchai Kirawittaya; Worakan Prompan; Anchalee Attachoo; Amornrat Pechdamrongsakul; Yanisa Intasorn; Prisana Hanchai; Chalerat Ounjareon; Putra Noisang
Journal:  J Med Assoc Thai       Date:  2008-10
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  4 in total

Review 1.  Safety of chloral hydrate sedation in dental practice for children: an overview.

Authors:  Sol Song; Miran Han; Jongbin Kim
Journal:  J Dent Anesth Pain Med       Date:  2020-06-24

Review 2.  Midazolam for sedation before procedures in adults and children: a systematic review update.

Authors:  Aaron Conway; Kristina Chang; Sebastian Mafeld; Joanna Sutherland
Journal:  Syst Rev       Date:  2021-03-05

3.  Analysis of application of dental sedation in attention deficit hyperactivity disorder (ADHD) patients using the Korean National Health Insurance data.

Authors:  Seong In Chi; Hyuk Kim; Kwang-Suk Seo
Journal:  J Dent Anesth Pain Med       Date:  2021-03-31

4.  Intranasal Dexmedetomidine Compared to a Combination of Intranasal Dexmedetomidine with Ketamine for Sedation of Children Requiring Dental Treatment: A Randomized Clinical Trial.

Authors:  Joji Sado-Filho; Patrícia Corrêa-Faria; Karolline A Viana; Fausto M Mendes; Keira P Mason; Luciane R Costa; Paulo S Costa
Journal:  J Clin Med       Date:  2021-06-27       Impact factor: 4.241
  4 in total

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