Literature DB >> 31447313

Ultrasound guided surgery under Dilutional Local Anaesthesia and no sedation in breast cancer patients.

Muhammad Nadeem1, Ajay Sahu2.   

Abstract

BACKGROUND: Breast cancer surgery under local anaesthesia (LA) can be challenging due to limitation of dose and quantity of anaesthetic agent that can be used safely. Elderly patients with breast cancer and with multiple co-morbidities are often prevented from having a standard treatment as they are considered unfit for general anaesthesia. We describe a technique of surgery under local anaesthesia without sedation that employs dilution to generate large volumes of LA and infiltration under ultrasound guidance.
METHODS: We present a case series by a single surgeon of breast cancer patients who underwent surgery under LA. 40 mls of 1% lignocaine with 1:200,000 adrenaline was diluted with 160 mls of normal saline to make a total of 200 mls, resulting in dilution to a concentration of 0.2% lignocaine. Radioactive isotope having been injected before patient's arrival in theatre, 1 ml of diluted anaesthetic solution is used with 2 mls of 2.5% patent blue to inject in the sub-areolar space. Local anaesthetic is infiltrated at operative site under ultrasound guidance using a long echogenic needle.
RESULTS: A total of 71 patients with breast cancer underwent surgery under the LA between September 2015 and October 2018. 64 (90%) patients had wide local excisions and 7 (10%) had mastectomies. All had axillary surgery, 65 (91.5%) had dual technique sentinel lymph node biopsy as a day case and 6 (8.5%) patients had axillary clearance. 8 patients had re excision (12.5%). All patients had '0' pain score and no postoperative analgesia was required in recovery. Local anaesthetic used did not exceed the maximum safe dose in any of the cases. One patient returned to theatre for postoperative wound bleeding. No other postoperative complication was observed.
CONCLUSION: Ultrasound guided infiltration allows accurate placement of large volume of diluted local anaesthetic solution safely and provides effective anaesthesia. Crown
Copyright © 2019. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Breast cancer; Local anaesthetic; Surgery; Ultrasound

Year:  2019        PMID: 31447313     DOI: 10.1016/j.surge.2019.06.006

Source DB:  PubMed          Journal:  Surgeon        ISSN: 1479-666X            Impact factor:   2.392


  4 in total

1.  Anesthetic effect of ultrasound-guided multiple-nerve blockade in modified radical mastectomy in patients with breast cancer.

Authors:  Haiyun Du; Xiang Liu; Feng Li; Zhouya Xue; Yuhai Li; Bin Qian
Journal:  Medicine (Baltimore)       Date:  2021-02-19       Impact factor: 1.817

Review 2.  Considerations for the Use of Local Anesthesia in the Frail Elderly: Current Perspectives.

Authors:  Philippe Cuvillon; Jean Yves Lefrant; Yann Gricourt
Journal:  Local Reg Anesth       Date:  2022-08-10

3.  Clinical Value of Total Intravenous Anesthesia with Sufentanil and Propofol in Radical Mastectomy.

Authors:  Lingyan Qu; Xiaoqing Wu
Journal:  Dis Markers       Date:  2022-08-05       Impact factor: 3.464

4.  Ropivacaine infiltration analgesia of the drainage exit site enhanced analgesic effects after breast Cancer surgery: a randomized controlled trial.

Authors:  Baona Wang; Tao Yan; Xiangyi Kong; Li Sun; Hui Zheng; Guohua Zhang
Journal:  BMC Anesthesiol       Date:  2020-10-06       Impact factor: 2.217

  4 in total

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