| Literature DB >> 31446716 |
Abstract
Summary Allergic rhinitis(AR), a common and frequente disease, has attracted global attention in recent years. The imbalance between Th1 and Th2 cellular immune responses is the immunological basis of AR. Studies have found that vitamin D plays an important role in the occurrence of AR, and IL-33/ST2 is a newly discovered cytokine and signaling pathway in AR. There are certain specific associations between vitamin D and IL-33/ST2 in the pathogenesis of AR. This paper mainly analyzes the studies on the expression of vitamin D, IL-33/ST2 and Th1/Th2 cytokines in AR, so as to clarify the role of the above two factors in the pathogenesis of AR. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.Entities:
Keywords: IL-33; rhinitis, allergic; sST2; vitamin D
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Year: 2019 PMID: 31446716 DOI: 10.13201/j.issn.1001-1781.2019.09.026
Source DB: PubMed Journal: Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi ISSN: 2096-7993