Literature DB >> 3144646

EDTA chelation therapy in chronic degenerative disease.

E Olszewer1, J P Carter.   

Abstract

A retrospective analysis of treatment results from 2870 patients, with various chronic degenerative and age-associated diseases, who were treated with di-sodium magnesium EDTA chelation therapy, suggests that the case against EDTA Chelation Therapy should be re-opened. Using qualitative but never-the-less standardized criteria for improvement, our analysis shows that EDTA Chelation Therapy resulted in "marked" improvement in 76.89% and "good" improvement in 16.56% of patients with ischemic heart disease; also, "marked" improvement in 91% and "good" improvement in 7.6% of patients with peripheral vascular disease and intermittent claudication. In a group of patients with cerebro-vascular and other degenerative cerebral diseases, 24% had "marked" improvement, and 30% had "good" improvement. Of four patients with scleroderma, three had "marked" improvement and one had "good" improvement. Seventy-five percent of all of the patients had "marked" improvement in "geriatric symptomatology of vascular origin". The authors recommend renewed study of EDTA Chelation Therapy. The possibility of a "tomato effect", i.e., a drug which works, but the majority of physicians believe that it doesn't work, needs to be ruled out. A favorable climate needs to be created, in which FDA-approved studies of its usefulness in treating peripheral vascular disease can take place.

Entities:  

Mesh:

Substances:

Year:  1988        PMID: 3144646     DOI: 10.1016/0306-9877(88)90082-5

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  8 in total

Review 1.  Chelation therapy for cardiovascular disease. Review and commentary.

Authors:  M R Lewin
Journal:  Tex Heart Inst J       Date:  1997

2.  A pilot double-blind study of sodium-magnesium EDTA in peripheral vascular disease.

Authors:  E Olszewer; F C Sabbag; J P Carter
Journal:  J Natl Med Assoc       Date:  1990-03       Impact factor: 1.798

3.  Design of the Trial to Assess Chelation Therapy (TACT).

Authors:  Gervasio A Lamas; Christine Goertz; Robin Boineau; Daniel B Mark; Theodore Rozema; Richard L Nahin; Jeanne A Drisko; Kerry L Lee
Journal:  Am Heart J       Date:  2012-01       Impact factor: 4.749

4.  Effect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: the TACT randomized trial.

Authors:  Gervasio A Lamas; Christine Goertz; Robin Boineau; Daniel B Mark; Theodore Rozema; Richard L Nahin; Lauren Lindblad; Eldrin F Lewis; Jeanne Drisko; Kerry L Lee
Journal:  JAMA       Date:  2013-03-27       Impact factor: 56.272

5.  Why the NIH Trial to Assess Chelation Therapy (TACT) should be abandoned.

Authors:  Kimball C Atwood; Elizabeth Woeckner; Robert S Baratz; Wallace I Sampson
Journal:  Medscape J Med       Date:  2008-05-13

Review 6.  Edetate Disodium-Based Treatment for Secondary Prevention in Post-Myocardial Infarction Patients.

Authors:  Gervasio A Lamas; Omar M Issa
Journal:  Curr Cardiol Rep       Date:  2016-02       Impact factor: 2.931

Review 7.  Potential Role of Metal Chelation to Prevent the Cardiovascular Complications of Diabetes.

Authors:  Rossana Calderon Moreno; Ana Navas-Acien; Esteban Escolar; David M Nathan; Jonathan Newman; John F Schmedtje; Denisse Diaz; Gervasio A Lamas; Vivian Fonseca
Journal:  J Clin Endocrinol Metab       Date:  2019-07-01       Impact factor: 6.134

Review 8.  Chelation Therapy in Patients With Cardiovascular Disease: A Systematic Review.

Authors:  Filippo Ravalli; Xavier Vela Parada; Francisco Ujueta; Rachel Pinotti; Kevin J Anstrom; Gervasio A Lamas; Ana Navas-Acien
Journal:  J Am Heart Assoc       Date:  2022-03-01       Impact factor: 6.106

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.