Literature DB >> 3144594

Controlled release of diphosphonates from synthetic polymers to inhibit calcification.

G Golomb1.   

Abstract

Calcification is the most frequent cause of the failure of bioprosthetic heart valves fabricated from glutaraldehyde pretreated porcine aortic valves or bovine pericardium. Formulation and evaluation of controlled-release drug delivery system to inhibit bioprosthetic heart valve calcification is reviewed.

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Year:  1987        PMID: 3144594     DOI: 10.1177/088532828700200205

Source DB:  PubMed          Journal:  J Biomater Appl        ISSN: 0885-3282            Impact factor:   2.646


  1 in total

1.  Bisacylphosphonates inhibit hydroxyapatite formation and dissolution in vitro and dystrophic calcification in vivo.

Authors:  G Golomb; A Schlossman; H Saadeh; M Levi; J M Van Gelder; E Breuer
Journal:  Pharm Res       Date:  1992-01       Impact factor: 4.200

  1 in total

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