Literature DB >> 31445840

Mesenchymal stem cells in allergic diseases: Current status.

He Li1, Yunzhe Tian1, Lihui Xie1, Xiuxing Liu1, Zhaohao Huang1, Wenru Su2.   

Abstract

Allergic diseases, which include asthma, allergic skin diseases, allergic rhinitis and allergic conjunctivitis, have already garnered worldwide public health attention over recent decades. Mesenchymal stem cells (MSCs) have gradually emerged as a potential method for treating allergic diseases due to their immunosuppressive characteristics, tissue repair ability and secretion of various biological factors. This potential of MSC-based therapy has been confirmed in clinical and preclinical studies, which report the therapeutic benefits of MSCs for various allergic diseases and explore the antiallergic mechanisms. In this review, we focus on the discoveries and biological mechanisms of MSCs as a therapeutic tool in allergic diseases. We discuss the challenges of conducting MSC studies as well as future directions.
Copyright © 2019 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Allergic disease; Asthma; Exosomes; Immunomodulation; Mesenchymal stem cells

Mesh：

Year:  2019        PMID： 31445840     DOI： 10.1016/j.alit.2019.08.001

Source DB:  PubMed          Journal:  Allergol Int        ISSN： 1323-8930            Impact factor:   5.836


  11 in total

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Review 2.  Therapeutic Targets in Allergic Conjunctivitis.

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3.  Classification models and SAR analysis on CysLT1 receptor antagonists using machine learning algorithms.

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Review 4.  Mesenchymal Stem Cells and Atopic Dermatitis: A Review.

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Review 5.  Exosomes: A Key Piece in Asthmatic Inflammation.

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6.  The CD4+CD25+FoxP3+ Regulatory T Cells Regulated by MSCs Suppress Plasma Cells in a Mouse Model of Allergic Rhinitis.

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7.  Conditioned Medium of Human Amniotic Epithelial Cells Alleviates Experimental Allergic Conjunctivitis Mainly by IL-1ra and IL-10.

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Review 9.  The Potential of Exosomes in Allergy Immunotherapy.

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Review 10.  New Therapeutic Approaches for Allergy: A Review of Cell Therapy and Bio- or Nano-Material-Based Strategies.

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Journal:  Pharmaceutics       Date:  2021-12-14       Impact factor: 6.321
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