Literature DB >> 31443669

Correction to: Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy.

Jia Wei1,2, Ling Ma2, Yi-Hui Lai3, Ruijie Zhang2, Huameng Li4, Chenglong Li5, Jiayuh Lin6.   

Abstract

In the original publication of this article [1], there is an error in Fig. 4A.

Entities:  

Year:  2019        PMID: 31443669      PMCID: PMC6706875          DOI: 10.1186/s13046-019-1381-y

Source DB:  PubMed          Journal:  J Exp Clin Cancer Res        ISSN: 0392-9078


Correction to: J Exp Clin Cancer Res https://doi.org/10.1186/s13046-019-1072-8 In the original publication of this article [1], there is an error in Fig. 4A.
Fig. 4

Bazedoxifene inhibits induction of STAT3 phosphorylation and cell proliferation by IL-11. a: DLD-1, HCT-116, and HCT-15 cells were starved in serum-free medium for 24 h and pre-treated with bazedoxifene (5~20 μM) for 2 h. Then, 50 ng/ml (DLD-1 cells) or 25 ng/ml IL-11 (HCT-116 and HCT-15 cells), 50 ng/ml OSM (DLD-1 cells) and 50 ng/ml IFN-γ (DLD-1 cells) were added for stimulation. The p-STAT3Y705, p-STAT1Y701, STAT3, STAT1 and GAPDH were assessed by western blot analysis.

The corrected Fig. 4A should be: Bazedoxifene inhibits induction of STAT3 phosphorylation and cell proliferation by IL-11. a: DLD-1, HCT-116, and HCT-15 cells were starved in serum-free medium for 24 h and pre-treated with bazedoxifene (5~20 μM) for 2 h. Then, 50 ng/ml (DLD-1 cells) or 25 ng/ml IL-11 (HCT-116 and HCT-15 cells), 50 ng/ml OSM (DLD-1 cells) and 50 ng/ml IFN-γ (DLD-1 cells) were added for stimulation. The p-STAT3Y705, p-STAT1Y701, STAT3, STAT1 and GAPDH were assessed by western blot analysis.
  1 in total

1.  Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy.

Authors:  Jia Wei; Ling Ma; Yi-Hui Lai; Ruijie Zhang; Huameng Li; Chenglong Li; Jiayuh Lin
Journal:  J Exp Clin Cancer Res       Date:  2019-02-08
  1 in total
  1 in total

1.  Inhibition of GP130/STAT3 and EMT by combined bazedoxifene and paclitaxel treatment in ovarian cancer.

Authors:  Sun-Ae Park; Lee Kyung Kim; Hye Min Park; Hee Jung Kim; Tae-Hwe Heo
Journal:  Oncol Rep       Date:  2022-01-14       Impact factor: 3.906

  1 in total

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