Literature DB >> 31442612

Energy coupling in ABC exporters.

Hendrik W van Veen1, Himansha Singh2, Kelvin Agboh2, Lisa A Fagg2, Dawei Guo2, Brendan Swain2, Robbin F de Kruijf2, Charlotte Guffick2.   

Abstract

Multidrug transporters are important and interesting molecular machines that extrude a wide variety of cytotoxic drugs from target cells. This review summarizes novel insights in the energetics and mechanisms of bacterial ATP-binding cassette multidrug transporters as well as recent advances connecting multidrug transport to ion and lipid translocation processes in other membrane proteins.
Copyright © 2019 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  ABC transporter; Bioenergetics; Multidrug transport; Transport mechanisms

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Year:  2019        PMID： 31442612     DOI： 10.1016/j.resmic.2019.08.003

Source DB:  PubMed          Journal:  Res Microbiol        ISSN： 0923-2508            Impact factor:   3.992


  2 in total

1.  A Conserved Motif in Intracellular Loop 1 Stabilizes the Outward-Facing Conformation of TmrAB.

Authors:  Cinthia R Millan; Martina Francis; Nitesh Kumar Khandelwal; Valery F Thompson; Tarjani M Thaker; Thomas M Tomasiak
Journal:  J Mol Biol       Date:  2021-01-29       Impact factor: 6.151

2.  Engineered MATE multidrug transporters reveal two functionally distinct ion-coupling pathways in NorM from Vibrio cholerae.

Authors:  Sagar Raturi; Asha V Nair; Keiko Shinoda; Himansha Singh; Boyan Bai; Satoshi Murakami; Hideaki Fujitani; Hendrik W van Veen
Journal:  Commun Biol       Date:  2021-05-11
  2 in total

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