Literature DB >> 31441565

Barriers to effective management of hepatitis C virus in people who inject drugs: Evidence from outpatient clinics.

Sabrina Molinaro1, Giuliano Resce1, Alfredo Alberti2, Massimo Andreoni3, Pietro P F D Egidio4, Claudio Leonardi5, Felice A Nava6, Patrizio Pasqualetti7, Stefano Villa8,9.   

Abstract

INTRODUCTION AND AIMS: People who inject drugs (PWID) constitute the largest reservoir of hepatitis C virus (HCV). Although effective medications are available and access to care is universal in Italy, the proportion of PWID receiving appropriate care remains low. DESIGN AND METHODS: To identify the major barriers for PWID to HCV treatment we surveyed a large sample of practitioners working in outpatient addiction centres (SerDs). The survey was conducted in two stages and involved 30.3% of SerDs operating in Italy. In the first, SerD physicians completed a questionnaire designed with a Delphi structure. In the second, SerD practitioners completed a targeted questionnaire to identify barriers to four SerD services in HCV management: screening, referral, treatment and harm reduction.
RESULTS: The first-stage questionnaire, in which a Delphi and RAND-UCLA method was used, revealed a lack of agreement among the physicians about barriers to health care. The more detailed second-stage questionnaire indicated the barriers to delivering specific SerD services. As regarded the delivery of all four services, the major reasons for treating <50% of patients were: physician and nurse understaffing, technical, economic and logistic issues. In contrast, the practitioners who responded that they follow protocol recommendations often deliver all four services to >50% of patients. DISCUSSION AND
CONCLUSIONS: HCV treatment remains out of reach for many PWID attending a drug treatment centre in Italy. To meet the World Health Organisation (WHO) target, there is a need to increase economic, technical and staff support at treatment centres using the protocols and the universal health care already in place.
© 2019 Australasian Professional Society on Alcohol and other Drugs.

Entities:  

Keywords:  drugs; hepatitis C virus; infection; people who inject drugs management

Mesh:

Year:  2019        PMID: 31441565     DOI: 10.1111/dar.12978

Source DB:  PubMed          Journal:  Drug Alcohol Rev        ISSN: 0959-5236


  7 in total

1.  Telemedicine Improves HCV Elimination among Italian People Who Use Drugs: An Innovative Therapeutic Model to Increase the Adherence to Treatment into Addiction Care Centers Evaluated before and during the COVID-19 Pandemic.

Authors:  Valerio Rosato; Riccardo Nevola; Vincenza Conturso; Pasquale Perillo; Davide Mastrocinque; Annalisa Pappalardo; Teresa Le Pera; Ferdinando Del Vecchio; Ernesto Claar
Journal:  Biology (Basel)       Date:  2022-05-24

2.  Hepatitis C virus cascade of care in the general population, in people with diabetes, and in substance use disorder patients.

Authors:  Olivera Djuric; Marco Massari; Marta Ottone; Giorgia Collini; Pamela Mancuso; Massimo Vicentini; Antonio Nicolaci; Angela Zannini; Alessandro Zerbini; Valeria Manicardi; Loreta A Kondili; Paolo Giorgi Rossi
Journal:  Infect Agent Cancer       Date:  2021-01-19       Impact factor: 2.965

3.  Progress toward closing gaps in the hepatitis C virus cascade of care for people who inject drugs in San Francisco.

Authors:  Ali Mirzazadeh; Yea-Hung Chen; Jess Lin; Katie Burk; Erin C Wilson; Desmond Miller; Danielle Veloso; Willi McFarland; Meghan D Morris
Journal:  PLoS One       Date:  2021-04-02       Impact factor: 3.240

4.  Peer-mediated HIV assisted partner services to identify and link to care HIV-positive and HCV-positive people who inject drugs: a cohort study protocol.

Authors:  Aliza Monroe-Wise; Loice Mbogo; Brandon Guthrie; David Bukusi; Betsy Sambai; Bhavna Chohan; John Scott; Peter Cherutich; Helgar Musyoki; Rose Bosire; Matthew Dunbar; Paul Macharia; Sarah Masyuko; Eduan Wilkinson; Tulio De Oliveira; Natasha Ludwig-Barron; Bill Sinkele; Joshua Herbeck; Carey Farquhar
Journal:  BMJ Open       Date:  2021-04-24       Impact factor: 2.692

5.  Meet-Test-Treat for HCV management: patients' and clinicians' preferences in hospital and drug addiction services in Italy.

Authors:  Massimo Andreoni; Nicola Coppola; Antonio Craxì; Stefano Fagiuoli; Ivan Gardini; Alessandra Mangia; Felice Alfonso Nava; Patrizio Pasqualetti
Journal:  BMC Infect Dis       Date:  2022-01-04       Impact factor: 3.090

6.  Hepatitis C virus burden: Treating and educating people without prejudice.

Authors:  Elettra Merola; Elisa Menotti; Giovanna Branz; Andrea Michielan; Sonia Seligmann; Annora Ratti; Flora Agugiaro; Luisa Moser; Giovanni Vettori; Anna Franceschini; William Mantovani; Riccardo Pertile; Giovanni de Pretis; Cecilia Pravadelli
Journal:  World J Hepatol       Date:  2022-07-27

7.  Increased Hepatitis C virus screening, diagnosis and linkage to care rates among people who use drugs through a patient-centered program from Italy.

Authors:  Alessandra Mangia; Maria Franca Rina; Antonio Canosa; Valeria Piazzolla; Maria Maddalena Squillante; Ernesto Agostinacchio; Giovanna Cocomazzi; Egidio Visaggi; Nazario Augello; Camilla Iannuzziello; Mattia Falcone; Angelo De Giorgi; Fausto Campanozzi
Journal:  United European Gastroenterol J       Date:  2021-10-26       Impact factor: 4.623

  7 in total

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